product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Neurogranin
catalog :
MBS142170
quantity :
0.002 mg
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142170
products type :
Recombinant Protein
products full name :
Recombinant Human Neurogranin
products short name :
Neurogranin
products name syn :
hng, RC3, Neurogranin, Ng, NRGN
other names :
neurogranin; Neurogranin; neurogranin; calmodulin-binding protein; protein kinase C substrate; neurogranin (protein kinase C substrate, RC3); RC3NEUG(55-78)
products gene name :
NRGN
other gene names :
NRGN; NRGN; RC3; hng; Ng
uniprot entry name :
NEUG_HUMAN
sequence length :
78
sequence :
MGSSHHHHHH SSGLVPRGSH MGSMDCCTEN ACSKPDDDIL DIPLDDPGAN AAAAKIQASF RGHMARKKIK SGERGRKGPG PGGPGGAGVA RGGAGGGPSG D.
purity :
Greater than 90% as determined by SDS-PAGE.
form :
NRGN protein solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH7.0), 30% glycerol 0.1mM PMSF and 1mM EDTA.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
other info1 :
Source: Escherichia Coli.
other info2 :
Physical Appearance: Sterile filtered colorless solution.
products categories :
CYTOKINES AND GROWTH FACTORS
products description :
NRGN Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 101 amino acids (1-78 a.a.) and having a molecular mass of 10.0kDa (molecular size on SDS-PAGE will appear higher). NRGN is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
ncbi gi num :
5453800
ncbi acc num :
NP_006167.1
ncbi gb acc num :
NM_006176.2
ncbi mol weight :
7,618 Da
ncbi summary :
Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq, Jul 2008]
uniprot summary :
neurogranin: Acts as a third messenger substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium. Belongs to the neurogranin family. Protein type: Cell development/differentiation. Chromosomal Location of Human Ortholog: 11q24. Cellular Component: intracellular. Molecular Function: calmodulin binding. Biological Process: nervous system development; signal transduction
size1 :
0.002 mg
price1 :
140 USD
size2 :
0.01 mg
price2 :
205
size3 :
1 mg
price3 :
5015
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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