product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Rat Insulin Like Growth Factor-1
catalog :
MBS142166
quantity :
0.01 mg
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142166
products type :
Recombinant Protein
products full name :
Recombinant Rat Insulin Like Growth Factor-1
products short name :
Insulin Like Growth Factor-1
products name syn :
IGF1 Rat; Insulin-Like Growth Factor 1 Rat Recombinant; Somatomedin C; IGF-I; IGFIA; IGF1
other names :
insulin-like growth factor I isoform a preproprotein; Insulin-like growth factor I; insulin-like growth factor I; IGF-I; somatomedin; insulin-like growth factor 1; Somatomedin
products gene name :
rIGF1
other gene names :
Igf1; Igf1; Igf-1; IGF-I
uniprot entry name :
IGF1_RAT
host :
E Coli
sequence length :
143
sequence :
GPETLCGAEL VDALQFVCGP RGFYFNKPTG YGSSIRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPTKSA.
purity :
Greater than 98.0% as determined by SDS-PAGE.
form :
The protein was lyophilized with no additives. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized IGF-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution IGFI should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized IGF1 in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: The ED50, was calculated 2 methods: 1. Stimulation of protein synthesis in rat L6 myoblasts ED50 was found to be < 30ng/ml corresponding to a Specific Activity of 33,334IU/mg. 2. Type 1 IGF receptor binding assay ED50 was found to be <10ng/ml corresponding to a Specific Activity of 100,000IU/mg.
products categories :
CYTOKINES AND GROWTH FACTORS; Growth Factors; Insulin-Like Growth Factor
products description :
Description: Insulin-Like Growth Factor I Rat Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 70 amino acids and having a molecular mass of 7.7kDa. IGF-I is purified by proprietary chromatographic techniques. Introduction: The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH; MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed 'sulfation factor,' which later became known as 'somatomedin' (Daughaday et al., 1972). Three main somatomedins have been characterized: somatomedin C (IGF1), somatomedin A (IGF2; MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986; Rosenfeld, 2003).
ncbi gi num :
163659885
ncbi acc num :
NP_001075946.2
ncbi gb acc num :
NM_001082477.2
uniprot acc num :
P08025
ncbi mol weight :
17,831 Da
ncbi pathways :
AMPK Signaling Pathway 989832!!AMPK Signaling Pathway 992181!!Adipogenesis Pathway 198479!!Aldosterone-regulated Sodium Reabsorption Pathway 130622!!Aldosterone-regulated Sodium Reabsorption Pathway 130590!!Androgen Receptor Signaling Pathway 198529!!Apoptosis Pathway 219785!!Dilated Cardiomyopathy Pathway 121476!!Dilated Cardiomyopathy Pathway 121285!!Endochondral Ossification Pathway 219771
ncbi summary :
growth factor; plays a major role in mammalian growth [RGD, Feb 2006]
size :
0.01 mg
price :
140 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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