product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Soluble Iinterleukin-2 Receptor alpha
catalog :
MBS142162
quantity :
1 mg
price :
3575 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142162
products type :
Recombinant Protein
products full name :
Recombinant Human Soluble Iinterleukin-2 Receptor alpha
products short name :
Soluble Iinterleukin-2 Receptor alpha
products name syn :
sIL 2R Human; Interleukin-2 alpha Soluble Receptor Human Recombinant; CD25; IL2R; TCGFR; IL-2RA; sIL-2RA; TAC antigen; sIL-2R; IDDM10; p55
other names :
interleukin-2 receptor subunit alpha; Interleukin-2 receptor subunit alpha; interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2R subunit alpha; TAC antigen; interleukin 2 receptor, alpha; TAC antigen; p55; CD_antigen: CD25
products gene name :
sIL 2R
other gene names :
IL2RA; IL2RA; p55; CD25; IL2R; TCGFR; IDDM10; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA
uniprot entry name :
IL2RA_HUMAN
host :
E Coli
sequence length :
272
purity :
Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
IL-2R His-Tag protein is supplied in 1x PBS and 50% glycerol pH 7.4. Sterile colorless liquid formulation.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. Please avoid freeze thaw cycles.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Interleukin
products description :
Description: Interleukin-2R Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 192 amino acids (22-213) corresponding to the mature IL2-R protein with an amino terminal hexahistidine tag.The IL-2R is purified by proprietary chromatographic techniques. Introduction: IL2-Ra is one of the three constituent subunits of the IL2 receptor. IL-2Ra is released into the serum after increased cellular expression such as increased activation of B and T cells. Clinical manifestations of IL2-Ra elevation include autoimmune conditions and some leukemias and lymphomas.
ncbi gi num :
4557667
ncbi acc num :
NP_000408.1
ncbi gb acc num :
NM_000417.2
uniprot acc num :
P01589
ncbi mol weight :
30,819 Da
ncbi pathways :
Arf6 Trafficking Events Pathway 137954!!Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway 137993!!Calcium Signaling In The CD4+ TCR Pathway 137941!!Cytokine Signaling In Immune System Pathway 366171!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Downstream Signaling In Naive CD8+ T Cells Pathway 138018!!Endocytosis Pathway 102279!!Endocytosis Pathway 102181!!G Beta:gamma Signalling Through PI3Kgamma Pathway 119540
ncbi summary :
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
size :
1 mg
price :
3575 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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