catalog number :
MBS142159
products type :
Recombinant Protein
products full name :
Recombinant Mouse Interleukin-4
products short name :
Interleukin-4
products name syn :
IL 4 Mouse; Interleukin-4 Mouse Recombinant; BCGF; BCDF; B cell stimulating factor; BSF-1; Lymphocyte stimulatory factor 1; IL-4; MGC79402; Binetrakin; Pitrakinra
other names :
interleukin-4; Interleukin-4; interleukin-4; B-cell IgG differentiation factor; B-cell growth factor 1; B-cell stimulatory factor 1; IGG1 induction factor; lymphocyte stimulatory factor 1; interleukin 4; B-cell IgG differentiation factor; B-cell growth factor 1; B-cell stimulatory factor 1; BSF-1; IGG1 induction factor; Lymphocyte stimulatory factor 1
products gene name :
mIL 4
other gene names :
Il4; Il4; Il-4; BSF-1; Il-4; IL-4; BSF-1
uniprot entry name :
IL4_MOUSE
sequence :
MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S.
purity :
Greater than 96.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
Lyophilized from a 0.2 um concentrated (1mg/ml) solution in PBS pH 7.4. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Interleukin-4 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution IL4 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Biological Activity: The ED50 as determined by the dose-dependant induction of HT-2 cell proliferation is less than 2 ng/ml corresponding to a Specific Activity of 500,000IU/mg.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Interleukin
products description :
Description: Interleukin-4 Mouse Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 120 amino acids and having a molecular mass of 13500 Dalton. The IL-4 is purified by proprietary chromatographic techniques. Introduction: Interleukin-4 is a pleiotropic cytokine produced primarily by activated T lymphocytes, basophils and mast cells. Multiple immune response-modulating functions are performed by IL-4 on a variety of cell types and it has an important role in the regulator of isotype switching, induction of IgE production in B lymphocytes and differentiation of precursor T helper cells. IL-4 binds to both membrane-bound and secreted soluble IL-4 receptors.
ncbi acc num :
NP_067258.1
ncbi gb acc num :
NM_021283.2
ncbi mol weight :
15,834 Da
ncbi pathways :
Allograft Rejection Pathway 83316!!Allograft Rejection Pathway 535!!Asthma Pathway 83313!!Asthma Pathway 532!!Autoimmune Thyroid Disease Pathway 83314!!Autoimmune Thyroid Disease Pathway 533!!Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!Cytokines And Inflammatory Response (BioCarta) Pathway 198283!!Fc Epsilon RI Signaling Pathway 83279