product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Mouse Stem Cell Factor
catalog :
MBS142152
quantity :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142152
products type :
Recombinant Protein
products full name :
Recombinant Mouse Stem Cell Factor
products short name :
Stem Cell Factor
products name syn :
SCF Mouse; Recombinant Mouse Stem Cell Factor; Kit ligand Precursor; C-kit ligand; SCF; Mast cell growth factor; MGF; SF; KL-1; Kitl; DKFZp686F2250; Hematopoietic growth factor KL; Steel factor
other names :
kit ligand; Kit ligand; kit ligand; C-kit ligand; Steel factor; cloud gray; grizzle-belly; hematopoietic growth factor KL; mast cell growth factor; stem cell factor; kit ligand; Hematopoietic growth factor KL; Mast cell growth factor; MGF; Steel factor; Stem cell factor; SCF; c-Kit ligandSoluble KIT ligand; sKITLG
products gene name :
mSCF
other gene names :
Kitl; Kitlg; Gb; SF; Sl; Clo; Con; Mgf; SCF; SLF; blz; Kitlg; contrasted; Kitl; Mgf; Sl; Slf; MGF; SCF; sKITLG
uniprot entry name :
SCF_MOUSE
host :
E Coli
sequence length :
273
sequence :
MKEICGNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV IQLSLSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVLC MEENAPKNIK ESPKRPETRS FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA.
purity :
Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
form :
Lyophilized from a concentrated (1mg/ml) solution in water containing 0.02% NaHCO3. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized KIT ligand although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution SCF should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Stem Cell Factor in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Protein Content: Protein quantitation was carried out by two independent methods:1. UV spectroscopy at 280 nm using the absorbency value of 0.52 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a standard solution of Stem Cell Factor as a Reference Standard. Biological Activity: The ED50 as determined by the dose-dependant stimulation of Human TF-1 cell line is < 10 ng/ml, corresponding to a Specific Activity of 1x105 IU/mg.
products categories :
CYTOKINES AND GROWTH FACTORS; Growth Factors; Stem Cell Factor
products description :
Description: Stem Cell Factor Mouse Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 165 amino acids and having a molecular mass of 18309 Dalton. The SCF is purified by proprietary chromatographic techniques. Introduction: Stem cell factor / KIT ligand (SCF) is a cytokine which binds CD117(c-Kit). SCF is also known as "steel factor" or "c-kit ligand". SCF exists in two forms, cell surface bound SCF and soluble (or free) SCF. Soluble SCF is produced by the cleavage of surface bound SCF by metalloproteases.SCF is a growth factor important for the survival, proliferation, and differentiation of hematopoietic stem cells and other hematopoietic progenitor cells. One of its roles is to change the BFU-E (burst-forming unit-erythroid) cells, which are the earliest erythrocyte precursors in the erythrocytic series, into the CFU-E (colony-forming unit-erythroid).
ncbi gi num :
7305267
ncbi acc num :
NP_038626.1
ncbi gb acc num :
NM_013598.2
uniprot acc num :
P20826
ncbi mol weight :
27,614 Da
ncbi pathways :
Adaptive Immune System Pathway 1110669!!Constitutive PI3K/AKT Signaling In Cancer Pathway 1111361!!Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!DAP12 Interactions Pathway 1110771!!DAP12 Signaling Pathway 1110772!!Disease Pathway 1111319!!Downstream Signal Transduction Pathway 1110451!!Downstream Signaling Events Of B Cell Receptor (BCR) Pathway 1110683!!Downstream Signaling Of Activated FGFR Pathway 1110382
size :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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