catalog number :
MBS142150
products type :
Recombinant Protein
products full name :
Recombinant Mouse Interleukin-1 beta
products short name :
Interleukin-1 beta
products name syn :
IL 1 beta Mouse; Interleukin-1 beta Mouse Recombinant; Catabolin; Lymphocyte-activating factor (LAF); Endogenous Pyrogen (EP); Leukocyte Endogenous Mediator (LEM); Mononuclear Cell Factor (MCF); IL1F2; IL-1 beta
other names :
interleukin-1 beta; Interleukin-1 beta; interleukin-1 beta; IL-1 beta; interleukin 1 beta; N/A
products gene name :
mIL 1 beta
other gene names :
Il1b; Il1b; Il-1b; IL-1beta; IL-1 beta
uniprot entry name :
IL1B_MOUSE
sequence :
MVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQGEPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRFVFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSS.
purity :
Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
Mouse IL-1b was lyophilized from a 0.2 um filtered concentrated (1.0mg/ml) solution in PBS, pH 7.5. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Interleukin-1b although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution IL1b should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Interleukin-1b in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: The ED50 as determined by the dose-dependant stimulation of mouse D10S cells was found to be less than 2.0 pg/ml, corresponding to a Specific Activity of 5.0 x 108 IU/mg.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Interleukin
products description :
Description: Interleukin-1 beta Mouse Recombinant produced in E Coli is a non-glycosylated, Polypeptide chain containing 153 amino acids and having a molecular mass of 17500 Dalton. The IL-1b is purified by proprietary chromatographic techniques. Introduction: Interleukin-1b is produced by activated macrophages, IL-1B stimulates thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity. IL1B proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
ncbi acc num :
NP_032387.1
ncbi gb acc num :
NM_008361.3
ncbi mol weight :
30,931 Da
ncbi pathways :
African Trypanosomiasis Pathway 194387!!African Trypanosomiasis Pathway 194323!!Alzheimer's Disease Pathway 83294!!Alzheimer's Disease Pathway 509!!Amoebiasis Pathway 167330!!Amoebiasis Pathway 167191!!Apoptosis Pathway 83257!!Apoptosis Pathway 470!!Chagas Disease (American Trypanosomiasis) Pathway 147810!!Chagas Disease (American Trypanosomiasis) Pathway 147795