protein

Recombinant Ovine Prolactin

MBS142117

0.01 mg

140 USD

Recombinant Protein

Recombinant Ovine Prolactin

Prolactin

Prolactin Ovine; Prolactin Ovine Recombinant; Mammotropin; Luteotropic hormone; Luteotropin; PRL; oProlactin

prolactin; Prolactin; prolactin

PRL; PRL; PRL

PRL_SHEEP

E Coli

240

The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Thr-Pro-Val-Cys-Pro.

Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.

The protein was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3. Sterile Filtered White lyophilized (freeze-dried) powder.

Lyophilized Prolactin although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Prl should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Solubility: It is recommended to reconstitute the lyophilized Prolactin in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Protein Content: Protein quantitation was carried out by two independent methods1. UV spectroscopy at 280 nm using the absorbency value of 0.85 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a calibrated solution of Prolactin as a Reference Standard. Biological Activity: Is fully biologically active as evidenced by inducing proliferation of Nb2 cells.

CYTOKINES AND GROWTH FACTORS; Growth Factors; Prolactin

Description: Prolactin Ovine Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 199 amino acids and having a molecular mass of 23 kDa. The Prolactin n is purified by proprietary chromatographic techniques. Introduction: Prolactin is a neuroendocrine hormone synthesized primarily by the pituitary gland but also a variety of other cell types including the placenta, brain and uterus. Its primary function is to promote and maintain lactation but has also been shown to have a role in breast cancer development, regulation of reproductive function and immunoregulation.

57164329

NP_001009306.1

NM_001009306.1

P01240

25,778 Da

Cytokine-cytokine Receptor Interaction Pathway (1030752); Cytokine-cytokine Receptor Interaction Pathway (460); Jak-STAT Signaling Pathway (1030801); Jak-STAT Signaling Pathway (488); Neuroactive Ligand-receptor Interaction Pathway (1030753); Neuroactive Ligand-receptor Interaction Pathway (462); PI3K-Akt Signaling Pathway (1030766); PI3K-Akt Signaling Pathway (692979); Prolactin Signaling Pathway (1030835); Prolactin Signaling Pathway (814248)

prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family. Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide; Cytokine

0.01 mg

140 USD

0.05 mg

205

1 mg

745