product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Ovine Growth Hormone
catalog :
MBS142114
quantity :
0.02 mg
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142114
products type :
Recombinant Protein
products full name :
Recombinant Ovine Growth Hormone
products short name :
Growth Hormone
products name syn :
GH Ovine; Growth Hormone Ovine Recombinant; GH1; GH; GHN; GH-N; hGH-N; Pituitary growth hormone; Growth hormone 1; Somatotropin
other names :
somatotropin; Somatotropin; somatotropin; growth hormone 12; Growth hormone
products gene name :
oGH
other gene names :
GH; GH1; GH1; N/A
uniprot entry name :
SOMA_SHEEP
host :
E Coli
sequence length :
217
sequence :
The sequence of the first five N-terminal amino acids was determined and was found to be Met-Ala-Phe-Pro-Ala.
purity :
Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
form :
The protein was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Growth Hormone although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution GH Ovine should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Growth Hormone in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Protein Content: Protein quantitation was carried out by two independent methods1. UV spectroscopy at 280 nm using the absorbency value of 0.7 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a calibrated solution of GH as a Reference Standard. Biological Activity: The activity as determined by the dose-dependant stimulation of the proliferation FDCP13B9 cells.
products categories :
CYTOKINES AND GROWTH FACTORS; Growth Factors; Growth Hormone
products description :
Description: Growth Hormone Ovine Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 200 amino acids and having a molecular mass of 22015 Dalton. The GH Ovine Recombinant is purified by proprietary chromatographic techniques. Introduction: GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
ncbi gi num :
57527824
ncbi acc num :
NP_001009315.2
ncbi gb acc num :
NM_001009315.3
uniprot acc num :
P67930
ncbi mol weight :
24,631 Da
ncbi pathways :
Jak-STAT Signaling Pathway 1030801!!Jak-STAT Signaling Pathway 488!!Neuroactive Ligand-receptor Interaction Pathway 1030753!!Neuroactive Ligand-receptor Interaction Pathway 462!!PI3K-Akt Signaling Pathway 1030766!!PI3K-Akt Signaling Pathway 692979
size :
0.02 mg
price :
140 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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