protein

Recombinant Human Creatine Kinase Muscle Type-1

MBS142067

0.01 mg

140 USD

Recombinant Protein

Recombinant Human Creatine Kinase Muscle Type-1

Creatine Kinase Muscle Type-1

CKMT1 Human; Creatine Kinase Muscle Type-1 Human Recombinant; Creatine kinase M-type; EC 2.7.3.2; Creatine kinase M chain; M-CK; CKM; CKMM; CKMMITI; CKM Type-1

creatine kinase M-type; Creatine kinase M-type; creatine kinase M-type; creatine kinase M chain; creatine kinase, muscle; Creatine kinase M chain; M-CKCreatine kinase M-type, N-terminally processed

CKM

CKM; CKM; CKMM; M-CK; CKMM

KCRM_HUMAN

Pichia Pastoris

381

Greater than 95.0% as determined by a) Analysis by RP-HPLC b) Analysis by SDS-PAGE

CKMT1 contains 0.01M Tris-HCl, 0.075M NaCl, 10mM beta-mercaptoethanol, 50% glycerol, 0.1% sodium azide, pH 7.2. Sterile Filtered colourless liquid formulation.

CKMT1 although stable at 15 degree C for 7 days, should be stored below -18 degree C. Please prevent freeze-thaw cycles.

Biological Activity: The biological activity measured by the enzymatic activity of Creatine phosphokinase procedure No.45-UV, 1IU-1 umole creatine phosphate was 537IU/mg at 37 degrees celsius corresponding to a Specific Activity of 1,863ng/ml.

PROTEIN KINASES; Enzymes; Creatin Kinases

Description: CKMT1 Human Recombinant without C-terminal Lysine on both chains produced in Pichia Pastoris is a glycosylated 47kDa polypeptide chain having an identical amino acid sequence compared to the native enzyme, purified under non-denaturing conditions and reacts with polyclonal antibodies to MM Isoenzyme in ELISA. The CKMT1 is purified by proprietary chromatographic techniques. Introduction: Creatine Kinase MM is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.

21536288

NP_001815.2

NM_001824.4

P06732

43,101 Da

Arginine And Proline Metabolism Pathway 82957!!Arginine And Proline Metabolism Pathway 323!!Creatine Metabolism Pathway 106192!!Creatine Pathway 413359!!Creatine Pathway 468234!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Amino Acids And Derivatives Pathway 106169!!Regulation Of Retinoblastoma Protein Pathway 137916!!Urea Cycle And Metabolism Of Amino Groups Pathway 198758

The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]

0.01 mg

140 USD