protein

Recombinant Human Creatine Kinase Brain

MBS142064

0.01 mg

140 USD

Recombinant Protein

Recombinant Human Creatine Kinase Brain

Creatine Kinase Brain

CKB Human; Creatine Kinase Brain Human Recombinant; Creatine kinase B-type; EC 2.7.3.2; Creatine kinase B chain; B-CK; CKB; CKBB; CKBBI

creatine kinase B-type; Creatine kinase B-type; creatine kinase B-type; creatine kinase B chain; creatine kinase-B; epididymis luminal protein 211; epididymis secretory protein Li 29; creatine kinase, brain; B-CK; Creatine kinase B chain

CKB

CKB; CKB; BCK; B-CK; CKBB; HEL-211; HEL-S-29; CKBB

KCRB_HUMAN

Pichia Pastoris

381

Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

CKBB Human contains 10Mm Bis-Tris-HCl pH-6.0, 50% glycerol, 0.5mM EDTA and 0.5mM DTT. Sterile Filtered colourless liquid formulation.

10ug/4ul

CKBB should be stored below -18 degree C. Please prevent freeze-thaw cycles.

Biological Activity: The biological activity measured by the enzymatic activity of Creatine phosphokinase procedure No.45-UV, 1IU-1 umole creatine phosphate was 854 IU/mg at 37 degrees celsius corresponding to a Specific Activity of 1,171ng/ml.

PROTEIN KINASES; Enzymes; Creatin Kinases

Description: CKBB Human Recombinant produced in Pichia Pastoris is a glycosylated polypeptide chain having an identical amino acid sequence compared to the native enzyme, purified under non-denaturing conditions and reacts with polyclonal antibodies to BB Isoenzyme in ELISA. The CKBB is purified by proprietary chromatographic techniques. Introduction: Creatine Kinase BB is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized.

21536286

NP_001814.2

NM_001823.4

P12277

42,644 Da

Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); Creatine Metabolism Pathway (106192); Creatine Pathway (413359); Creatine Pathway (468234); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Amino Acids And Derivatives Pathway (106169); Urea Cycle And Metabolism Of Amino Groups Pathway (198758); Creatine-phosphate Biosynthesis Pathway (545319)

The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]

CKB: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family. Protein type: EC 2.7.3.2; Amino Acid Metabolism - arginine and proline; Kinase, other. Chromosomal Location of Human Ortholog: 14q32. Cellular Component: mitochondrion; cytosol. Molecular Function: protein binding; creatine kinase activity; ATP binding. Biological Process: substantia nigra development; creatine metabolic process; cellular chloride ion homeostasis; phosphorylation

0.01 mg

140 USD

0.05 mg

205

1 mg

980