product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Interleukin-8 (1-77) (CXCL8), His Tag
catalog :
MBS142052
quantity :
0.01 mg
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142052
products type :
Recombinant Protein
products full name :
Recombinant Human Interleukin-8 (1-77) (CXCL8), His Tag
products short name :
Interleukin-8
products name syn :
IL 8 Human (1-77), His; Interleukin-8 (1-77 a.a) Human Recombinant (CXCL8), His Tag; IL-8; CXCL8; Monocyte-derived neutrophil chemotactic factor; MDNCF; T-cell chemotactic factor; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil-activating peptide; MONAP; Emoctakin; K60; NAF; LECT; LUCT; 3-10C; LYNAP; SCYB8; TSG-1; AMCF-I; b-ENAP; IL 8 (1-77), His
other names :
interleukin-8; Interleukin-8; interleukin-8; T-cell chemotactic factor; alveolar macrophage chemotactic factor I; beta endothelial cell-derived neutrophil activating peptide; beta-thromboglobulin-like protein; emoctakin; granulocyte chemotactic protein 1; interleukin 8; lung giant cell carcinoma-derived chemotactic protein; lymphocyte derived neutrophil activating peptide; monocyte-derived neutrophil chemotactic factor; monocyte-derived neutrophil-activating peptide; neutrophil-activating peptide 1; small inducible cytokine subfamily B, member 8; tumor necrosis factor-induced gene 1; chemokine (C-X-C motif) ligand 8; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factorCleaved into the following 7 chains:MDNCF-aAlternative name(s):GCP/IL-8 protein IV; IL8/NAP1 form I
products gene name :
IL-8
other gene names :
CXCL8; CXCL8; IL8; NAF; GCP1; LECT; LUCT; NAP1; GCP-1; LYNAP; MDNCF; MONAP; NAP-1; IL8; IL-8; GCP-1; MDNCF; MONAP; NAP-1; LYNAP; NAF
uniprot entry name :
IL8_HUMAN
host :
E Coli
sequence length :
99
purity :
Greater than 95.0% as determined by SDS-PAGE.
form :
IL8 His is supplied in 10mM Tris-HCl pH 8, 250mM NaCl and 50% glycerol. Sterile Filtered clear solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. Please avoid freeze thaw cycles.
products categories :
CHEMOKINES; Chemokines; Interleukin-8 (CXCL8)
products description :
Description: Interleukin-8 Human Recombinant produced in E Coli is single, a non-glycosylated, Polypeptide chain containing 77 amino acids fragment (23-99) and having a total molecular mass of 13.7kDa with an amino-terminal hexahistidine tag. The IL-8 His is purified by proprietary chromatographic techniques. Introduction: Interleukin-8 (IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies. When first encountering an antigen, the primary cells to encounter it are the macrophages who phagocytose the particle. Upon processing, they release chemokines to signal other immune cells to come in to the site of inflammation. IL-8 is one such chemokine. It serves as a chemical signal that attracts neutrophils at the site of inflammation, and therefore is also known as Neutrophil Chemotactic Factor.
ncbi gi num :
10834978
ncbi acc num :
NP_000575.1
ncbi gb acc num :
NM_000584.3
uniprot acc num :
P10145
ncbi mol weight :
11,338 Da
ncbi pathways :
ATF-2 Transcription Factor Network Pathway 138006!!ATF4 Activates Genes Pathway 530772!!Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Bladder Cancer Pathway 83115!!Bladder Cancer Pathway 527!!Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway 137993!!Cellular Senescence Pathway 905991!!Cellular Responses To Stress Pathway 645258!!Chagas Disease (American Trypanosomiasis) Pathway 147809
ncbi summary :
The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008]
size :
0.01 mg
price :
140 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
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