product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Mouse Macrophage Inflammatory protein-3 beta (CCL19)
catalog :
MBS142048
quantity :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142048
products type :
Recombinant Protein
products full name :
Recombinant Mouse Macrophage Inflammatory protein-3 beta (CCL19)
products short name :
Macrophage Inflammatory protein-3 beta
products name syn :
MIP 3b Mouse; Macrophage Inflammatory Protein-3 Beta Mouse Recombinant (CCL19); Small inducible cytokine A19; CCL19; Macrophage inflammatory protein 3 beta; MIP-3- beta; EBI1-ligand chemokine; ELC; Beta chemokine exodus-3; CK beta-11; chemokine (C-C motif) ligand 19; CKb11; MIP3B; MIP-3b; SCYA19; MGC34433; Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1-ligand chemokine
other names :
C-C motif chemokine 19; C-C motif chemokine 19; C-C motif chemokine 19; EBI-1 ligand chemokine; EBI1 ligand chemokine; EBI1-ligand chemokine; EBV-induced molecule 1 ligand chemokine; chemokine CCL19; epstein-Barr virus-induced molecule 1 ligand chemokine; small inducible cytokine A19; small-inducible cytokine A19; chemokine (C-C motif) ligand 19; Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1 ligand chemokine; ELC; Small-inducible cytokine A19
products gene name :
mMIP 3b
other gene names :
Ccl19; Ccl19; ELC; CKb11; MIP3B; Scya19; exodus-3; Elc; Scya19; EBI1 ligand chemokine; ELC
uniprot entry name :
CCL19_MOUSE
host :
E Coli
sequence length :
108
sequence :
The sequence of the first five N-terminal amino acids was determined and was found to be, Gly-Ala-Asn-Asp-Ala.
purity :
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
The CCL19 was lyophilized from a concentrated (1mg/ml) solution in water containing no additives. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized MIP-3b although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution CCL19 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Macrophage Inflammatory Protein-3b in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Protein Content: Protein quantitation was carried out by two independent methods:1. UV spectroscopy at 280 nm using the absorbency value of 0.91 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a calibrated solution of MIP-3b as a Reference Standard. Biological Activity: The Activity is calculated by the ability to chemoattract Human mature dendritic cells using a concentration range of 8-80 ng/ml.
products categories :
CHEMOKINES; Chemokines; MIP
products description :
Description: Macrophage Inflammatory Protein-3 beta Mouse Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 83 amino acids and having a molecular mass of 9216 Dalton. The MIP-3b is purified by proprietary chromatographic techniques. Introduction: Chemokine (C-C motif) ligand 19 (CCL19) is a small cytokine belonging to the CC chemokine family that is also known as EBI1 ligand chemokine (ELC) and macrophage inflammatory protein-3-beta (MIP-3-beta). CCL19 is expressed abundantly in thymus and lymph nodes, with moderate levels in trachea and colon and low levels in stomach, small intestine, lung, kidney and spleen. The gene for CCL19 is located on human chromosome 9. This chemokine elicits its effects on its target cells by binding to the chemokine receptor chemokine receptor CCR7. It attracts certain cells of the immune system, including dendritic cells and antigen-engaged B cells.
ncbi gi num :
6755422
ncbi acc num :
NP_036018.1
ncbi gb acc num :
NM_011888.2
uniprot acc num :
O70460
ncbi mol weight :
11,911 Da
ncbi pathways :
Chemokine Receptors Bind Chemokines Pathway 1110501!!Chemokine Signaling Pathway 99271!!Chemokine Signaling Pathway 672435!!Chemokine Signaling Pathway 96864!!Class A/1 (Rhodopsin-like Receptors) Pathway 1110499!!Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway 1111486!!Disease Pathway 1111319!!G Alpha (i) Signalling Events Pathway 1110530
size :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!