catalog number :
MBS142047
products type :
Recombinant Protein
products full name :
Recombinant Porcine Interleukin-8 (1-72) (CXCL8)
products short name :
Interleukin-8
products name syn :
IL 8 Porcine; Interleukin-8 (1-72 a.a) Porcine Recombinant (CXCL8); IL-8; CXCL8; Monocyte-derived neutrophil chemotactic factor; MDNCF; T-cell chemotactic factor; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil-activating peptide; MONAP; Emoctakin; K60; NAF; LECT; LUCT; 3-10C; LYNAP; SCYB8; TSG-1; AMCF-I; b-ENAP; Alveolar macrophage chemotactic factor I
other names :
interleukin-8; Interleukin-8; interleukin-8; C-X-C motif chemokine 8; IL-8; alveolar macrophage chemotactic factor I; alveolar macrophage-derived chemotactic factor-I; chemokine (C-X-C motif) ligand 8; Alveolar macrophage chemotactic factor I; AMCF-I; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8
products gene name :
pIL 8
other gene names :
IL8; CXCL8; CXCL8; AMCF-I; IL8; IL-8; AMCF-I
uniprot entry name :
IL8_PIG
sequence :
ARVSAELRCQ CINTHSTPFH PKFIKELRVI ESGPHCENSE IIVKLVNGKE VCLDPKEKWV QKVVQIFLKR TEKQQQQQ.
purity :
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
Lyophilized from a 0.2 um filtered concentrated solution in 1xPBS, pH 7.4. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Interleukin-8 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution CXCL8 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Interleukin 8 in sterile 18M-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: The biological activity was determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration range of 20-200 ng/ml.
products categories :
CHEMOKINES; Chemokines; Interleukin-8 (CXCL8)
products description :
Description: Interleukin-8 Porcine Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 78 amino acids and having a molecular mass of 9.1kDa. The IL8 is purified by proprietary chromatographic techniques. Introduction: Interleukin-8 (IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies. When first encountering an antigen, the primary cells to encounter it are the macrophages who phagocytose the particle. Upon processing, they release chemokines to signal other immune cells to come in to the site of inflammation. IL-8 is one such chemokine. It serves as a chemical signal that attracts neutrophils at the site of inflammation, and therefore is also known as Neutrophil Chemotactic Factor.
ncbi acc num :
NP_999032.1
ncbi gb acc num :
NM_213867.1
ncbi mol weight :
11,633 Da
ncbi pathways :
Amoebiasis Pathway 167313!!Amoebiasis Pathway 167191!!Bladder Cancer Pathway 84522!!Bladder Cancer Pathway 527!!Cellular Senescence Pathway 1125456!!Cellular Responses To Stress Pathway 1125444!!Chagas Disease (American Trypanosomiasis) Pathway 147807!!Chagas Disease (American Trypanosomiasis) Pathway 147795!!Chemokine Receptors Bind Chemokines Pathway 1124657!!Chemokine Signaling Pathway 98758