catalog number :
MBS142001
products type :
Recombinant Protein
products full name :
Recombinant Phospholipase A2 P00630 Bee Venom Protein
products short name :
Phospholipase A2
products name syn :
Phospholipase A2; Phospholipase A2 P00630 Bee Venom Protein Recombinant; Phospholipase A2; Phosphatidylcholine 2-acylhydrolase; Allergen Api m I; Api m 1
other names :
phospholipase A2; Phospholipase A2; phospholipase A2; allergen Api m 1; allergen Api m I; phosphatidylcholine 2-acylhydrolase; phospholipase A2<; Allergen Api m I; Phosphatidylcholine 2-acylhydrolase; Allergen: Api m 1
products gene name :
PA2-BVP
other gene names :
Pla2; bvPLA2; bvPLA2; GB13351; bvPLA2
uniprot entry name :
PA2_APIME
purity :
Protein is >90% pure as determined by 10% SDS-PAGE. Purified by proprietary chromatographic technique.
form :
20mM Tris-HCl, pH 7.2, 1.5M urea and 50% glycerol.
storage stability :
Phospholipase A2 although stable at 4 degree C for 1 week, should be stored below -18 degree C. Please prevent freeze thaw cycles.
products categories :
ALLERGY PROTEINS; Recombinant Proteins; Allergy
products description :
Description: The E Coli derived recombinant protein contains phospholipase P00630 bee venom protein epitopes, 26-162 amino acids. Introduction: Bee venom phospholipase A2 (PLA) is the main allergen in the bee sting allergy. Bee venom phospholipase A2 (BV-PLA2) is a hydrolytic enzyme which specifically cleaves the sn-2 acyl bond of phospholipids at the lipid/water interface. BV-PLA2 is a 1416-kDa glycoprotein, consisting of 134 amino acids and displaying a single carbohydrate side chain at the residue Asn13. It is also held to be responsible for some systemic anaphylactic reactions in bee venom sensitized individuals. BV-PLA2 presents 3 peptide and a glycopeptide T cell epitopes, which are recognized by both allergic and non-allergic bee venom sensitized subjects. PLA is able to elicit both IgE mediated allergy and normal immunity to bee sting which usually is associated with high affinity IgG4 anti-PLA antibodies.
ncbi acc num :
NP_001011614.1
ncbi gb acc num :
NM_001011614.1
ncbi mol weight :
19,058 Da