catalog number :
MBS141023
products full name :
Polyclonal Rabbit Anti Human Activin-A
products short name :
Activin-A
products name syn :
Activin-A Antibody; Activin-A, Polyclonal Rabbit Anti-Human Antibody; Inhba; Inhibin beta A; FSH releasing protein; Activin-A
other names :
activin-A, partial
purity :
Purified IgG prepared by affinity chromatography on protein G.
form :
Lyophilized from a sterile filtered (0.2 um) solution containing phosphate buffered saline. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Store at -20 degree C. For long term storage freezes in working aliquots at -20 degree C. Repeated freezing and thawing is not recommended.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
Activin-A antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. In order to detect Human Activin A by indirect ELISA a dilution of at least 1:1,000 of the Activin A antibody is required. Activin A antibody, in conjunction with compatible secondary reagents (anti rabbit AP conjugated), allows the detection of 0.2-1 ng /well of Human Activin A. In order to detect human Activin A by WB analysis this IgG can be used in a dilution of 1:1,000.
other info1 :
Neutralization: To yield one-half maximal inhibition (ND50) of the biological activity of Activin A (7.5ng/ml), a concentration of 60-200ng/ml of the Activin-A antibody is required.
other info2 :
Solubility: Add 0.1 ml of distilled water and let the lyophilized pellet dissolve completely. Immunogen: Recombinant human Activin-A produced in plants.
products categories :
ANTI-HUMAN CYTOKINES; Polyclonal Antibodies
products description :
Introduction: Activins are homodimers or heterodimers of the different beta subunit isoforms, part of the TGFbeta family. Mature Activin A has two 116 amino acids residues betaA subunits (betaA-betaA). Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, haematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells.
ncbi acc num :
AAB32779.1