catalog number :
MBS140369
products full name :
Mouse Anti Human B-Cell Leukemia/Lymphoma 2
products short name :
B-Cell Leukemia/Lymphoma 2
products name syn :
BCL2 Antibody; B-Cell Leukemia/Lymphoma 2, Mouse Anti Human; Apoptosis regulator Bcl-2; BCL2; B-cell CLL/lymphoma 2; Bcl-2
other names :
Bcl2; Bcl2; B-cell leukemia/lymphoma 2; B-cell leukemia/lymphoma 2a; zBlp2; B-cell CLL/lymphoma 2a
products gene name :
BCL2
other gene names :
bcl2a; bcl2
isotype :
IgG2b heavy chain and k light chain
purity :
BCL2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
form :
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
storage stability :
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles. 12 months at -20 degree C. 1 month at 4 degree C.
tested application :
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
app notes :
BCL2 antibody has been tested by ELISA, Western blot, and Immunofluorescence analyses to assure specificity and reactivity. Since applications vary, however, each investigation should be titrated by a reagent to obtain optimal results. Recommended dilution range for Western blot analysis and Immunofluorescence is 1:250 ~ 500. Recommended starting dilution is 1:500.
other info2 :
Immunogen: Anti-human BCL2 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human BCL2 amino acids 1-211 purified from E Coli.
products categories :
MONOCLONAL/POLYCLONAL ANTIBODIES, MISCELLANEOUS ANTIBODIES; Monoclonal Antibodies
products description :
Introduction: BCL2 gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
ncbi acc num :
NP_001025424.1
ncbi gb acc num :
NM_001030253.2
ncbi pathways :
Adrenergic Signaling In Cardiomyocytes Pathway 908262!!Adrenergic Signaling In Cardiomyocytes Pathway 909696!!Apoptosis Pathway 921011!!Apoptosis Pathway 83637!!Apoptosis Pathway 470!!B Cell Receptor Signaling Pathway 198947!!FAS Pathway And Stress Induction Of HSP Regulation 198973!!Focal Adhesion Pathway 119265!!Focal Adhesion Pathway 478!!IL-2 Signaling Pathway 198953