catalog number : 
MBS140320
products full name : 
Mouse Anti Human Toll-like receptor 2
products short name : 
Toll-like receptor 2
products name syn : 
TLR2 Antibody; Toll-like receptor 2, Mouse Anti Human; Toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4; CD282; TLR2; TIL4
other names : 
toll-like receptor 2; Toll-like receptor 2; toll-like receptor 2; toll/interleukin 1 receptor-like 4; toll/interleukin-1 receptor-like protein 4; toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4; CD_antigen: CD282
products gene name : 
TLR2
other gene names : 
TLR2; TLR2; TIL4; CD282; TIL4
uniprot entry name : 
TLR2_HUMAN
isotype : 
IgG1 heavy chain and kappa light chain
purity : 
TLR2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
form : 
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.  Sterile filtered colorless solution.
storage stability : 
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.  12 months at -20 degree C. 1 month at 4 degree C.
tested application : 
ELISA (EIA), Western Blot (WB)
app notes : 
TLR2 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500.
other info2 : 
Immunogen: Anti-human TLR2 mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TLR2 amino acids 221-384 purified from E Coli.
products categories : 
MONOCLONAL/POLYCLONAL ANTIBODIES, MISCELLANEOUS ANTIBODIES; Monoclonal Antibodies
products description : 
Introduction:  TLR2 belongs to the Toll-like receptor (TLR) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) which are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
ncbi acc num : 
NP_003255.2
ncbi gb acc num : 
NM_003264.3
ncbi mol weight : 
89,838 Da
ncbi pathways : 
Activated TLR4 Signalling Pathway  106400!!Amoebiasis Pathway  167324!!Amoebiasis Pathway  167191!!Beta Defensins Pathway  530759!!Chagas Disease (American Trypanosomiasis) Pathway  147809!!Chagas Disease (American Trypanosomiasis) Pathway  147795!!Defensins Pathway  530757!!Hepatitis B Pathway  694606!!Herpes Simplex Infection Pathway  377873!!Herpes Simplex Infection Pathway  377865
ncbi summary : 
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq, Jul 2008]