product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse Anti Human Neuregulin1 isoform HRG-beta3
catalog :
MBS140289
quantity :
0.02 mg
price :
205 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Pk1G13AT
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS140289
products type :
Antibody
products full name :
Mouse Anti Human Neuregulin1 isoform HRG-beta3
products short name :
Neuregulin1 isoform HRG-beta3
products name syn :
NRG1 (HRG-beta3) Antibody; Neuregulin1 isoform HRG-beta3, Mouse Anti Human; NRG1 (HRG-beta3)
other names :
pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1c; Pro-neuregulin-1, membrane-bound isoform; pro-neuregulin-1, membrane-bound isoform; glial growth factor; heregulin, alpha (45kD, ERBB2 p185-activator); neu differentiation factor; pro-NRG1; sensory and motor neuron derived factor; neuregulin 1; Acetylcholine receptor-inducing activity; ARIA; Breast cancer cell differentiation factor p45; Glial growth factor; Heregulin; HRG; Neu differentiation factor; Sensory and motor neuron-derived factor
products gene name :
NRG1
other gene names :
NRG1; NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2; GGF; HGL; HRGA; NDF; SMDF; Pro-NRG1; ARIA; HRG
uniprot entry name :
NRG1_HUMAN
clonality :
Monoclonal
isotype :
IgG1 heavy chain and kappa light chain
clone :
Pk1G13AT
host :
Mouse
sequence length :
607
purity :
NRG1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
form :
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
storage stability :
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles. 12 months at -20 degree C. 1 month at 4 degree C.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
NRG1 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 2,000. Recommended starting dilution is 1:1,000.
other info2 :
Immunogen: Anti-human NRG1 mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NRG1 amino acids 20-241 purified from E Coli.
products categories :
ANTI-HUMAN CYTOKINES; Monoclonal Antibodies; Anti Human Cytokine
products description :
Introduction: NRG1 is one of 4 proteins in the neuregulin family which act on the EGFR family of receptors. NRG1 was initially identified as a 44kDa glycoprotein that interacts with the ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. In various brain areas, NRG1 is expressed at synaptic regions and its processing can be regulated by neuronal activity. The HRG-beta3variant of NRG1, along with HRG-alpha, beta1 and beta2 variants, was identified in various normal tissues and cancer cell lines.
ncbi gi num :
236461509
ncbi acc num :
NP_001153467.1
ncbi gb acc num :
NM_001159995.1
ncbi mol weight :
46,226 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Cardiac Progenitor Differentiation Pathway 712094!!Constitutive PI3K/AKT Signaling In Cancer Pathway 685535!!DAP12 Interactions Pathway 685549!!DAP12 Signaling Pathway 685550!!Disease Pathway 530764!!Downregulation Of ERBB2:ERBB3 Signaling Pathway 530740!!Downstream Signal Transduction Pathway 106385!!Downstream Signaling Events Of B Cell Receptor (BCR) Pathway 576250!!Downstream Signaling Of Activated FGFR Pathway 160957
ncbi summary :
The protein encoded by this gene is a membrane glycoprotein that that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Jun 2014]
size :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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