catalog number :
MBS140273
products full name :
Mouse Anti Human Interferon Regulatory Factor-5
products short name :
Interferon Regulatory Factor-5
products name syn :
IRF5 Antibody; Interferon Regulatory Factor-5, Mouse Anti Human; Interferon regulatory factor 5; IRF-5; IRF5; SLEB10
other names :
interferon regulatory factor 5 isoform b; Interferon regulatory factor 5; interferon regulatory factor 5; interferon regulatory factor 5
products gene name :
IRF5
other gene names :
IRF5; IRF5; SLEB10; IRF-5
uniprot entry name :
IRF5_HUMAN
isotype :
IgG1 heavy chain and kappa light chain
purity :
IRF5 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
form :
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
storage stability :
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles. 12 months at -20 degree C. 1 month at 4 degree C.
tested application :
ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
app notes :
IRF5 antibody has been tested by ELISA, Western blot, IP, and immunohistochemical analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1:1,000. Recommended starting dilution is 1:1,000.
other info2 :
Immunogen: Anti-human IRF5 mAb, is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with Recombinant human IRF5 amino acids 176-240 purified from E Coli.
products categories :
ANTI-HUMAN CYTOKINES; Monoclonal Antibodies; Anti Human Cytokine
products description :
Introduction: IRF5 belongs to the interferon regulatory factor (IRF) family, which is a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats.
ncbi acc num :
NP_001092097.2
ncbi gb acc num :
NM_001098627.3
ncbi mol weight :
17,020 Da
ncbi pathways :
Apoptosis Pathway 198797!!Cytokine Signaling In Immune System Pathway 366171!!Direct P53 Effectors Pathway 137939!!Immune System Pathway 106386!!Interferon Signaling Pathway 187103!!Interferon Alpha/beta Signaling Pathway 187104!!Interferon Gamma Signaling Pathway 187106!!Regulation Of Toll-like Receptor Signaling Pathway 920955!!Senescence And Autophagy Pathway 198780!!Toll-like Receptor Signaling Pathway 83076
ncbi summary :
This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Mar 2010]