antibody

Mouse Anti Human Glucose-6-Phosphate Dehydrogenase

MBS140252

0.02 mg

205 USD

monoclonal

mouse

nonconjugated

PAT2F6AT

Antibody

Mouse Anti Human Glucose-6-Phosphate Dehydrogenase

Glucose-6-Phosphate Dehydrogenase

G6PD Antibody; Glucose-6-Phosphate Dehydrogenase, Mouse Anti Human; G6PD; G6PD1; Glucose-6-phosphate 1-dehydrogenase

glucose-6-phosphate 1-dehydrogenase isoform a; Glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate dehydrogenase

G6PD

G6PD; G6PD; G6PD1; G6PD

G6PD_HUMAN

Monoclonal

IgG2b heavy chain and kappa light chain

PAT2F6AT

Mouse

545

G6PD antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.

1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.

For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles. 12 months at -20 degree C. 1 month at 4 degree C.

Immunogen: Anti-human G6PD mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human G6PD amino acids 35-506 purified from E Coli.

MONOCLONAL ANTIBODIES, ANTI-HUMAN ENZYMES; Monoclonal Antibodies; Anti Human Enzyme

Introduction: G6PD is the rate-limiting enzyme of the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells by maintaining the level of NADPH. G6PD converts glucose-6-phosphate into 6-phosphoglucono-delta-lactone and at the same time produces NADPH. The NADPH maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. G6PD deficiency causes acute hemolytic anemia, neonatal jaundice or acute hemolysis. G6PD is a cytosolic enzyme encoded by an X-linked gene whose main function is to produce NADPH, a crucial electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD produces pentose sugars for nucleic acid synthesis and is a main producer of NADPH reducing power.

109389365

NP_000393.4

NM_000402.4

62,468 Da

Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Central Carbon Metabolism In Cancer Pathway 1059538!!Central Carbon Metabolism In Cancer Pathway 1084231!!Disease Pathway 530764!!Glutathione Metabolism Pathway 82973!!Glutathione Metabolism Pathway 198824!!Glutathione Metabolism Pathway 343!!Glycogen Storage Diseases Pathway 1127581!!Metabolic Pathways 132956

This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

0.02 mg

205 USD