catalog number :
MBS140224
products full name :
Mouse Anti Human Cathepsin H
products short name :
Cathepsin H
products name syn :
Cathepsin H Antibody; Cathepsin H, Mouse Anti Human; Cathepsin H; CTSH; CPSB; ACC-4; ACC-5; MGC1519; minichain; DKFZp686B24257; Cathepsin H
other names :
pro-cathepsin H preproprotein; Pro-cathepsin H; pro-cathepsin H; N-benzoylarginine-beta-naphthylamide hydrolase; aleurain; cathepsin B3; cathepsin BA; cathepsin H
other gene names :
CTSH; CTSH; ACC4; ACC5; CPSB; ACC-4; ACC-5; minichain; CPSB
uniprot entry name :
CATH_HUMAN
isotype :
IgG2a heavy chain and kappa light chain
purity :
Cathepsin H antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
form :
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
storage stability :
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles. 12 months at -20 degree C. 1 month at 4 degree C.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
Cathepsin H antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 2,000. Recommended starting dilution is 1:1,000.
other info2 :
Immunogen: Anti-human Cathepsin H mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human Cathepsin H amino acids 23-335 purified from E Coli.
products categories :
MONOCLONAL ANTIBODIES, ANTI-HUMAN ENZYMES; Monoclonal Antibodies; Anti Human Enzyme
products description :
Introduction: Cathepsin H is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. Cathepsin H is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. Cathepsin H, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of the Cathepsin H gene has been associated with malignant progression of prostate tumors.
ncbi acc num :
NP_004381.2
ncbi gb acc num :
NM_004390.3
ncbi mol weight :
37,394 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Immune System Pathway 106386!!Lysosome Pathway 99052!!Lysosome Pathway 96865!!MHC Class II Antigen Presentation Pathway 645290
ncbi summary :
The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. [provided by RefSeq, Mar 2010]