Mouse Anti Human Betaine Homocysteine S-Methyltransferase | MyBioSource MBS140215 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Mouse Anti Human Betaine Homocysteine S-Methyltransferase

catalog :

MBS140215

quantity :

0.005 mg

price :

140 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

P3D6AT

reactivity :

human

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS140215

products type :

Antibody

products full name :

Mouse Anti Human Betaine Homocysteine S-Methyltransferase

products short name :

Betaine Homocysteine S-Methyltransferase

products name syn :

BHMT Antibody; Betaine Homocysteine S-Methyltransferase, Mouse Anti Human; BHMT; Betaine Homocysteine S-Methyltransferase 1; BHMT1

other names :

betaine--homocysteine S-methyltransferase 1; Betaine--homocysteine S-methyltransferase 1; betaine--homocysteine S-methyltransferase 1; epididymis secretory sperm binding protein Li 61p; betaine--homocysteine S-methyltransferase

products gene name :

BHMT

other gene names :

BHMT; BHMT; BHMT1; HEL-S-61p

uniprot entry name :

BHMT1_HUMAN

clonality :

Monoclonal

isotype :

IgG2a heavy chain and kappa light chain

clone :

P3D6AT

host :

Mouse

sequence length :

406

purity :

BHMT antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.

form :

1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. Sterile filtered colorless solution.

storage stability :

For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles. 12 months at -20 degree C. 1 month at 4 degree C.

tested application :

ELISA (EIA), Western Blot (WB)

app notes :

BHMT antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 2,000. Recommended starting dilution is 1:1,000.

other info2 :

Immunogen: Anti-human BHMT mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human BHMT amino acids 1-406 purified from E Coli.

products categories :

MONOCLONAL ANTIBODIES, ANTI-HUMAN ENZYMES; Monoclonal Antibodies; Anti Human Enzyme

products description :

Introduction: Betaine-homocysteine methyltransferase (BHMT) is a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. BHMT displays differential expression in a model of liver cirrhosis.

ncbi gi num :

157266337

ncbi acc num :

NP_001704.2

ncbi gb acc num :

NM_001713.2

ncbi mol weight :

44,998 Da

ncbi pathways :

Cysteine And Methionine Metabolism Pathway (104488); Cysteine And Methionine Metabolism Pathway (103421); Glycine, Serine And Threonine Metabolism Pathway (82949); Glycine, Serine And Threonine Metabolism Pathway (313); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Amino Acids And Derivatives Pathway (106169); One Carbon Metabolism Pathway (198756); Sulfur Amino Acid Metabolism Pathway (530753); Trans-sulfuration And One Carbon Metabolism Pathway (920958)

ncbi summary :

This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed. [provided by RefSeq, Jul 2008]

uniprot summary :

BHMT: Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. Protein type: EC 2.1.1.5; Amino Acid Metabolism - glycine, serine and threonine; Methyltransferase; Amino Acid Metabolism - cysteine and methionine. Chromosomal Location of Human Ortholog: 5q14.1. Cellular Component: protein complex; cytoplasm; cytosol. Molecular Function: betaine-homocysteine S-methyltransferase activity; homocysteine S-methyltransferase activity; zinc ion binding; protein complex binding. Biological Process: S-methylmethionine cycle; protein amino acid methylation; betaine catabolic process; sulfur amino acid metabolic process; S-adenosylmethionine metabolic process; response to organic nitrogen; betaine metabolic process; regulation of homocysteine metabolic process

size1 :

0.005 mg

price1 :

140 USD

size2 :

0.02 mg

price2 :

205

size3 :

0.1 mg

price3 :

505

more info or order :

MyBioSource product webpage