catalog number :
MBS140211
products full name :
Mouse Anti Human Acyl-Coenzyme A Thioesterase 11
products short name :
Acyl-Coenzyme A Thioesterase 11
products name syn :
ACOT11 Antibody; Acyl-Coenzyme A Thioesterase 11, Mouse Anti Human; Acyl-coenzyme A thioesterase 11; Acyl-CoA thioesterase 11; Acyl-CoA thioester hydrolase 11; Brown fat-inducible thioesterase; BFIT; Adipose-associated thioesterase; ACOT11; BFIT; KIAA0707; THEA; BFIT1; BFIT2; THEM1; STARD14
other names :
acyl-coenzyme A thioesterase 11 isoform 1; Acyl-coenzyme A thioesterase 11; acyl-coenzyme A thioesterase 11; START domain containing 14; StAR-related lipid transfer (START) domain containing 14; acyl-CoA thioester hydrolase 11; adipose-associated thioesterase; brown fat-inducible thioesterase; thioesterase superfamily member 1; thioesterase, adipose associated; acyl-CoA thioesterase 11; Acyl-CoA thioester hydrolase 11; Adipose-associated thioesterase; Brown fat-inducible thioesterase; BFIT
products gene name :
ACOT11
other gene names :
ACOT11; ACOT11; BFIT; THEA; THEM1; STARD14; BFIT; KIAA0707; THEA; Acyl-CoA thioesterase 11; BFIT
uniprot entry name :
ACO11_HUMAN
isotype :
IgG2b heavy chain and kappa light chain
purity :
ACOT11 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
form :
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
storage stability :
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles. 12 months at -20 degree C. 1 month at 4 degree C.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
ACOT11 antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:500 ~ 1:2,000 and immunohistochemistry analysis is 1:50~100. Recommended starting dilution for Western blot is 1:1,000 and Immunohistochemistry is 1:100.
other info2 :
Immunogen: Anti-human ACOT11 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human ACOT11 amino acids 19-250 purified from E Coli.
products categories :
MONOCLONAL ANTIBODIES, ANTI-HUMAN ENZYMES; Monoclonal Antibodies; Anti Human Enzyme
products description :
Introduction: ACOT11 is a protein with acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Expression of a similar murine protein in brown adipose tissue is induced by cold exposure and repressed by warmth. Expression of the mouse ACOT11 has been linked to obesity, with higher expression found in obesity-resistant mice compared with obesity-prone mice.
ncbi acc num :
NP_056362.1
ncbi gb acc num :
NM_015547.3
ncbi mol weight :
67,152 Da
ncbi summary :
This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]