catalog number :
MBS140209
products full name :
Mouse Anti Human 26S proteasome non-ATPase regulatory subunit 11
products short name :
26S proteasome non-ATPase regulatory subunit 11
products name syn :
PSMD11 Antibody; 26S proteasome non-ATPase regulatory subunit 11, Mouse Anti Human; 26S proteasome non-ATPase regulatory subunit 11; 26S proteasome regulatory subunit S9; 26S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit p44.5; PSMD11; S9; Rpn6; p44.5; MGC3844
other names :
Psmd11 protein, partial; 26S proteasome non-ATPase regulatory subunit 11; 26S proteasome non-ATPase regulatory subunit 11; 26S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit S9; 26S proteasome regulatory subunit p44.5; proteasome (prosome, macropain) 26S subunit, non-ATPase, 11; 26S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit S9; 26S proteasome regulatory subunit p44.5
products gene name :
PSMD11
other gene names :
Psmd11; Psmd11; S9; P44.5; C78232; 1700089D09Rik; 1810019E17Rik; 2610024G20Rik; 2810055C24Rik
uniprot entry name :
PSD11_MOUSE
isotype :
IgG1 heavy chain and kappa light chain
purity :
PSMD11 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
form :
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
storage stability :
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles. 12 months at -20 degree C. 1 month at 4 degree C.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
PSMD11 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:250 ~ 1000. Recommended starting dilution is 1:250.
other info2 :
Immunogen: Anti-human PSMD11 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PSMD11 amino acids 1-422 purified from E Coli.
products categories :
MONOCLONAL ANTIBODIES, ANTI-HUMAN ENZYMES; Monoclonal Antibodies; Anti Human Enzyme
products description :
Introduction: The 26S proteasome is a multicatalytic proteinase complex with a well ordered structure composed of two complexes- a 20S core and a 19S regulator. PSMD11 is a non-ATPase subunit of the 19S regulator. The 20S core is composed of four rings of 28 non-identical subunits; two rings are composed of 7 alpha subunits and two rings are composed of 7 beta subunits. The 19S regulator is composed of a base that contains six ATPase subunits and two non-ATPase subunits, and a lid that contains up to ten non-ATPase subunits. Proteasomes are spread throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An indispensable function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
ncbi acc num :
AAH55457.1
ncbi mol weight :
47,437 Da
ncbi pathways :
AMER1 Mutants Destabilize The Destruction Complex Pathway 1111443!!APC Truncation Mutants Are Not K63 Polyubiquitinated Pathway 1111438!!APC Truncation Mutants Have Impaired AXIN Binding Pathway 1111439!!APC/C-mediated Degradation Of Cell Cycle Proteins Pathway 1110158!!APC/C:Cdc20 Mediated Degradation Of Securin Pathway 1110169!!APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway 1110164!!APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway 1110171!!APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway 1110165!!AUF1 (hnRNP D0) Destabilizes MRNA Pathway 1111177!!AXIN Missense Mutants Destabilize The Destruction Complex Pathway 1111442