product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse Anti Human Heat Shock Protein 27
catalog :
MBS140204
quantity :
0.02 mg
price :
205 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
P2A5AT
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS140204
products type :
Antibody
products full name :
Mouse Anti Human Heat Shock Protein 27
products short name :
Heat Shock Protein 27
products name syn :
HSP27 Antibody; Heat Shock Protein 27, Mouse Anti Human; HSPB1; CMT2F; HMN2B; HSP27; HSP28; HSP25; Heat shock protein beta-1; Heat shock 27 kDa protein; Stress-responsive protein 27; SRP27; HS.76067; DKFZp586P1322
other names :
heat shock protein beta-1; Heat shock protein beta-1; heat shock protein beta-1; 28 kDa heat shock protein; HSP 27; epididymis secretory protein Li 102; estrogen-regulated 24 kDa protein; heat shock 27 kDa protein; heat shock 27kD protein 1; stress-responsive protein 27; heat shock 27kDa protein 1; 28 kDa heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27
products gene name :
HSP27
other gene names :
HSPB1; HSPB1; CMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS.76067; HEL-S-102; HSP27; HSP28; HspB1; HSP 27; SRP27
uniprot entry name :
HSPB1_HUMAN
clonality :
Monoclonal
isotype :
IgG1 heavy chain and kappa light chain
clone :
P2A5AT
host :
Mouse
sequence length :
205
purity :
HSP27 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
form :
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. Sterile Filtered colorless solution.
storage stability :
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles. 12 months at -20 degree C. 1 month at 4 degree C.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
HSP27 antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:1,000~1:2,000 and immunohistochemistry analysis is 1:50~100. Recommended starting dilution for Western blot is 1:1,000 and Immunohistochemistry is 1:50.
other info2 :
Immunogen: Anti-human HSP27 mAb, is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HSP27 amino acids 1-205 purified from E Coli.
products categories :
MONOCLONAL ANTIBODIES, ANTI-HUMAN HEAT SHOCK PROTEINS; Monoclonal Antibodies; Anti Human Heat Shock Protein
products description :
Introduction: HSP27 (also known as the Estrogen-Regulated 24K protein, and hsp 28) is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures, toxic metals, drugs and oxidants. Also, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPKAP kinase 2 and the stress-activated protein kinase SAPK2 (p38).
ncbi gi num :
4504517
ncbi acc num :
NP_001531.1
ncbi gb acc num :
NM_001540.3
ncbi mol weight :
22,783 Da
ncbi pathways :
AUF1 (hnRNP D0) Destabilizes MRNA Pathway 187212!!Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Epstein-Barr Virus Infection Pathway 585562!!Epstein-Barr Virus Infection Pathway 587115!!FAS Pathway And Stress Induction Of HSP Regulation 198894!!Gene Expression Pathway 105937!!IL-3 Signaling Pathway 198881!!IL-6 Signaling Pathway 198864!!MAPK Signaling Pathway 198779
ncbi summary :
The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). [provided by RefSeq, Oct 2008]
size :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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