Mouse Anti Human Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 | MyBioSource MBS140198 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Mouse Anti Human Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1

catalog :

MBS140198

quantity :

0.02 mg

price :

205 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

P4G1AT

reactivity :

human

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS140198

products type :

Antibody

products full name :

Mouse Anti Human Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1

products short name :

Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1

products name syn :

LYVE1 Antibody; Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1, Mouse Anti Human; Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor; LYVE-1; Cell surface retention sequence-binding protein 1; CRSBP-1; Hyaluronic acid receptor; Extracellular link domain-containing protein

other names :

lymphatic vessel endothelial hyaluronic acid receptor 1; Lymphatic vessel endothelial hyaluronic acid receptor 1; lymphatic vessel endothelial hyaluronic acid receptor 1; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; extracellular link domain containing 1; extracellular link domain-containing 1; extracellular link domain-containing protein 1; lymphatic vessel endothelial hyaluronan receptor 1; Cell surface retention sequence-binding protein 1; CRSBP-1; Extracellular link domain-containing protein 1; Hyaluronic acid receptor

products gene name :

LYVE1

other gene names :

LYVE1; LYVE1; HAR; XLKD1; LYVE-1; CRSBP-1; CRSBP1; HAR; XLKD1; LYVE-1; CRSBP-1

uniprot entry name :

LYVE1_HUMAN

clonality :

Monoclonal

isotype :

IgG2b heavy chain and kappa light chain

clone :

P4G1AT

host :

Mouse

sequence length :

322

purity :

LYVE1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.

form :

1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.

storage stability :

For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles. 12 months at -20 degree C. 1 month at 4 degree C.

tested application :

ELISA (EIA), Western Blot (WB)

app notes :

LYVE1 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:1,000.

other info2 :

Immunogen: Anti-human LYVE1 mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human LYVE1 amino acids 25-235 purified from E Coli.

products categories :

MONOCLONAL ANTIBODIES, ANTI-HUMAN ENZYMES; Monoclonal Antibodies; Anti Human Enzyme

products description :

Introduction: LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.

ncbi gi num :

40549451

ncbi acc num :

NP_006682.2

ncbi gb acc num :

NM_006691.3

ncbi mol weight :

35,213 Da

ncbi pathways :

Defective B3GAT3 Causes JDSSDHD Pathway 1127588!!Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway 1127592!!Defective B4GALT7 Causes EDS, Progeroid Type Pathway 1127587!!Defective CHST14 Causes EDS, Musculocontractural Type Pathway 1127591!!Defective CHST3 Causes SEDCJD Pathway 1127590!!Defective CHST6 Causes MCDC1 Pathway 1127593!!Defective CHSY1 Causes TPBS Pathway 1127589!!Defective EXT1 Causes Exostoses 1, TRPS2 And CHDS Pathway 1127594!!Defective EXT2 Causes Exostoses 2 Pathway 1127595!!Defective PAPSS2 Causes SEMD-PA Pathway 1127586

ncbi summary :

This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. [provided by RefSeq, Jul 2008]

size :

0.02 mg

price :

205 USD

more info or order :

MyBioSource product webpage