antibody

Mouse Anti Human Angiopoietin Like Protein 3

MBS140164

0.02 mg

255 USD

monoclonal

mouse

nonconjugated

P1D10AT

western blot, ELISA, enzyme immunoassay

Antibody

Mouse Anti Human Angiopoietin Like Protein 3

Angiopoietin Like Protein 3

ANGPTL3 Antibody; Angiopoietin Like Protein 3, Mouse Anti Human; Angiopoietin 5; ANGPT5; ANGPTL3

angiopoietin-related protein 3 preproprotein; Angiopoietin-related protein 3; angiopoietin-related protein 3; angiopoietin 5; angiopoietin-like 3; Angiopoietin-5; ANG-5; Angiopoietin-like protein 3

ANGPTL3

ANGPTL3; ANGPTL3; ANL3; ANG-5; FHBL2; ANGPT5; ANGPT5; ANG-5

ANGL3_HUMAN

Monoclonal

IgG1 heavy chain and kappa light chain

P1D10AT

Mouse

460

ANGPTL3 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.

1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.

For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles. 12 months at -20 degree C. 1 month at 4 degree C.

ELISA (EIA), Western Blot (WB)

ANGPTL3 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 2,000. Recommended starting dilution is 1:1,000.

Immunogen: Anti-human ANGPTL3 mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with Recombinant human ANGPTL3 amino acids 243-460 purified from E Coli.

ANTI-HUMAN CYTOKINES; Monoclonal Antibodies; Anti Human Cytokine

Introduction: Angiopoietin-like proteins ANGPTL3 and ANGPTL4 are secreted proteins mainly expressed in liver that have been demonstrated to regulate triglyceride metabolism by inhibiting the lipolysis of triglyceride-rich lipoproteins. ANGPTL3 is structurally similar to angiopoietins, which are vascular endothelial growth factors. The experimental results show that Angptl3 and Angptl4 function to regulate circulating triglyceride levels during different nutritional states and therefore play a role in lipid metabolism during feeding/fasting through differential inhibition of Lipoprotein lipase (LPL). Using deletion mutants of Angiopoietin 5 human, it was demonstrated that the N-terminal domain containing fragment - (17207) and not the C-terminal fibrinogen-like domain containing fragment - (207460) increased the plasma triglyceride levels in mice.

7656888

NP_055310.1

NM_014495.3

53,637 Da

Integrins In Angiogenesis Pathway 137999

This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metablism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Feb 2013]

0.02 mg

255 USD