catalog number :
MBS140143
products full name :
Mouse Anti Human CD44 Biotinylated
products short name :
CD44 Biotinylated
products name syn :
CD44 Antibody, Biotin; CD44, Mouse Anti-Human Biotin; MDU2; MDU3; MIC4; CDW44; CSPG8; HCELL; HUTCH-I; Phagocytic glycoprotein I; PGP-1; Extracellular matrix receptor-III; ECMR-III; Hermes antigen; Hyaluronate receptor; Heparan sulfate proteoglycan; Epican) CDw44; CD44 Biotin
other names :
CD44 antigen isoform 1; CD44 antigen; CD44 antigen; GP90 lymphocyte homing/adhesion receptor; Hermes antigen; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; epican; extracellular matrix receptor III; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; homing function and Indian blood group system; hyaluronate receptor; phagocytic glycoprotein 1; CD44 molecule (Indian blood group); CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; CD_antigen: CD44
products gene name :
CD44
other gene names :
CD44; CD44; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III; LHR; MDU2; MDU3; MIC4; ECMR-III; PGP-1; PGP-I
uniprot entry name :
CD44_HUMAN
concentration :
1mg/ml in PBS (after reconstitution).
storage stability :
Lyophilized: store at 4 degree C. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C.
other info2 :
Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Immunogen: Purified human T-Cells. Antibody Properties: Staining antibody. For staining, use 5-10 ul/1,000,000 cells. Available Conjugates: This antibody is also available conjugated to biotin and FITC. For staining with biotin or FITC-conjugated antibody use 5-10 ul/106 cells.
products categories :
MONOCLONAL ANTIBODIES, ANTI-HUMAN LYMPHOCYTES; Monoclonal Antibodies; Anti Human Lymphocyte
products description :
Introduction: CD44 is a cell-surface glycoprotein that plays a role in cell-cell interactions, cell adhesion and migration. CD44 is a receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. CD44 participates in a wide variety of cellular functions such as lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. CD44 and CD49d are putative activity markers and CD44 a potential novel therapeutic target in multiple sclerosis. Increased CD44 antigen is associated with relapses in non-small cell lung cancers.
ncbi acc num :
NP_000601.3
ncbi gb acc num :
NM_000610.3
ncbi mol weight :
15,635 Da
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway 106062!!Cytokine Signaling In Immune System Pathway 366171!!Defective B3GAT3 Causes JDSSDHD Pathway 1127588!!Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway 1127592!!Defective B4GALT7 Causes EDS, Progeroid Type Pathway 1127587!!Defective CHST14 Causes EDS, Musculocontractural Type Pathway 1127591!!Defective CHST3 Causes SEDCJD Pathway 1127590!!Defective CHST6 Causes MCDC1 Pathway 1127593!!Defective CHSY1 Causes TPBS Pathway 1127589!!Defective EXT1 Causes Exostoses 1, TRPS2 And CHDS Pathway 1127594
ncbi summary :
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]