catalog number :
MBS140137
products full name :
Hamster Anti Mouse CD28 Biotinylated
products short name :
CD28 Biotinylated
products name syn :
CD28 Antibody, Biotin; CD28, Hamster Anti-Mouse, Biotinylated; CD28 Biotin
other names :
T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28; CD28 antigen; CD_antigen: CD28
products gene name :
CD28
other gene names :
Cd28; Cd28
uniprot entry name :
CD28_MOUSE
concentration :
1mg/ml in PBS (after reconstitution).
storage stability :
Lyophilized: store at 4 degree C. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C.
other info2 :
Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Immunogen: Purified mouse purified mouse LN T cells. Antibody Properties: Blocking and staining antibody. For staining, use 10 ul/1,000,000 cells. Titer for blocking T cell activation should be determined by the investigator. Available Conjugates: This antibody is only available non-conjugated to FITC.
products categories :
MONOCLONAL ANTIBODIES, ANTI-MOUSE LYMPHOCYTES; Monoclonal Antibodies; Anti Mouse Lymphocyte
products description :
Introduction: CD28 co-stimulation is necessary for CD4 positive T-cell proliferation & survival, interleukin-2 production, and T-helper type-2 development. Human post-thymic regulatory T cells require CD28 co-stimulation to expand and maintain potent suppressive function in vivo. Apoptosis plays a key role in the age-related decline of CD28 expression and in immunosenescence.
ncbi acc num :
NP_031668.3
ncbi gb acc num :
NM_007642.4
ncbi mol weight :
25,243 Da
ncbi pathways :
Adaptive Immune System Pathway 1110669!!Allograft Rejection Pathway 83316!!Allograft Rejection Pathway 535!!Autoimmune Thyroid Disease Pathway 83314!!Autoimmune Thyroid Disease Pathway 533!!CD28 Co-stimulation Pathway 1110676!!CD28 Dependent PI3K/Akt Signaling Pathway 1110677!!CD28 Dependent Vav1 Pathway 1110678!!Cell Adhesion Molecules (CAMs) Pathway 83266!!Cell Adhesion Molecules (CAMs) Pathway 480