catalog number :
MBS140128
products full name :
Mouse Anti Human CD11b Biotinylated
products short name :
CD11b Biotinylated
products name syn :
CD11b Antibody, Biotin; CD11b, Mouse Anti-Human, Biotin; Integrin alpha-M; Cell surface glycoprotein MAC-1 subunit alpha; CR-3 alpha chain; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b antigen; ITGAM; CR3A; MO1A; CD11B; MAC-1; MAC1A; MGC117044; CD11b Biotin
other names :
CD11b, partial; CD11b; integrin alpha-M; CD11b
products gene name :
CD11b
other gene names :
ITGAM; CD11b; CD11B
uniprot entry name :
Q28984_PIG
purity :
Ion exchange column.
concentration :
1mg/ml in PBS (after reconstitution).
storage stability :
Lyophilized: store at 4 degree C. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C.
other info2 :
Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Immunogen: Purified human PBL Monocytes. Antibody Properties: Blocking and staining antibody. For staining, use 10 ul/1,000,000 cells. Titer for blocking LPS binding should be determined by the investigator. Available Conjugates: This antibody is also available unconjugated and conjugated to FITC. For staining with biotin or FITC-conjugated antibody use 5-10 ul/1,000,000 cells.
products categories :
MONOCLONAL ANTIBODIES, ANTI-HUMAN LYMPHOCYTES; Monoclonal Antibodies; Anti Human Lymphocyte
products description :
Introduction: Integrins are heterodimeric integral membrane proteins consisting of an ? chain and a ? chain. CD11b is an I-domain including ? integrin combines with the ? 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor also called MAC1. The ? M beta 2 integrin is crucial in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
ncbi acc num :
AAB16869.1
ncbi mol weight :
102,441 Da
ncbi pathways :
Amoebiasis Pathway 167313!!Amoebiasis Pathway 167191!!Cell Adhesion Molecules (CAMs) Pathway 84481!!Cell Adhesion Molecules (CAMs) Pathway 480!!Cell Surface Interactions At The Vascular Wall Pathway 1124973!!Extracellular Matrix Organization Pathway 1125418!!Hematopoietic Cell Lineage Pathway 84490!!Hematopoietic Cell Lineage Pathway 489!!Hemostasis Pathway 1124941!!Immune System Pathway 1125064