product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse Anti p53
catalog :
MBS140121
quantity :
0.1 mg
price :
375 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PP53SHG
reactivity :
human
application :
western blot, immunoprecipitation
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS140121
products type :
Antibody
products full name :
Mouse Anti p53
products short name :
p53
products name syn :
p53 Antibody; p53, Mouse Antibody
other names :
cellular tumor antigen p53 isoform a; Cellular tumor antigen p53; cellular tumor antigen p53; antigen NY-CO-13; mutant tumor protein 53; p53 tumor suppressor; phosphoprotein p53; transformation-related protein 53; tumor protein p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
products gene name :
p53
other gene names :
TP53; TP53; P53; BCC7; LFS1; TRP53; P53
uniprot entry name :
P53_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
PP53SHG
host :
Mouse
sequence length :
393
form :
1xPBS & 50% glycerol. Sterile Filtered solution.
tested application :
Western Blot (WB), Immunoprecipitation (IP)
app notes :
Western Blotting: 2ug/ml.
products categories :
MONOCLONAL/POLYCLONAL ANTIBODIES, MISCELLANEOUS ANTIBODIES; Monoclonal Antibodies
products description :
Description: Monoclonal antibodies are produced by immunizing mouse with full length His-tagged p53 protein. Introduction: p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
ncbi gi num :
120407068
ncbi acc num :
NP_000537.3
ncbi gb acc num :
NM_000546.5
ncbi mol weight :
24,401 Da
ncbi pathways :
AMPK Signaling Pathway 198868!!Activation Of BH3-only Proteins Pathway 105658!!Activation Of NOXA And Translocation To Mitochondria Pathway 105660!!Activation Of PUMA And Translocation To Mitochondria Pathway 105661!!Alzheimers Disease Pathway 672448!!Amyotrophic Lateral Sclerosis (ALS) Pathway 920975!!Amyotrophic Lateral Sclerosis (ALS) Pathway 83099!!Amyotrophic Lateral Sclerosis (ALS) Pathway 511!!Apoptosis Pathway 198797!!Apoptosis Pathway 83060
ncbi summary :
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
size :
0.1 mg
price :
375 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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