catalog number :
MBS140119
products full name :
Mouse Anti Myc
products short name :
Myc
products name syn :
Myc Antibody; Myc, Mouse Antibody; MYC; CMYC; C-MYS; V-MYC; P64
other names :
p110; P110; p110; p19 MA; p10; CA; MYC; P110
other gene names :
Amvgp1
uniprot entry name :
O56221_9RETR
form :
1xPBS & 50% glycerol.
tested application :
Western Blot (WB), Immunoprecipitation (IP)
app notes :
Western Blotting: 0.5 ug/ml.
products categories :
MONOCLONAL/POLYCLONAL ANTIBODIES, MISCELLANEOUS ANTIBODIES; Monoclonal Antibodies
products description :
Description: Monoclonal antibodies are produced by immunizing mouse with synthetic peptide (EQKLISEEDL) coupled to KLH. Introduction: c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
ncbi acc num :
NP_955602.1
ncbi gb acc num :
NC_001866.1
ncbi mol weight :
94,260 Da