product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse Anti MHC Class I (H-2K)
catalog :
MBS140072
quantity :
0.5 mg
price :
230 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
NYRmH-2K
reactivity :
human
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS140072
products type :
Antibody
products full name :
Mouse Anti MHC Class I (H-2K)
products short name :
MHC Class I
products name syn :
MHC Class I, H-2K Antibody; MHC Class I, (H-2K) Mouse Antibody
other names :
MHC class I; MHC class I; MHC class I
products gene name :
MHC Class I
other gene names :
gamr-UA-c24
uniprot entry name :
O98279_GADMO
clonality :
Monoclonal
isotype :
IgG2b
clone :
NYRmH-2K
host :
Mouse
sequence length :
236
specificity :
Recognizes most mouse H-2K haplotypes (k,p,q,r,s). Does NOT react with H-2kd.
purity :
Ion exchange column.
concentration :
1mg/ml in PBS (after reconstitution).
storage stability :
Lyophilized: store at 4 degree C. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C.
other info2 :
Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Immunogen: Purified mouse LN cells (C57Bl/6 anti-BALB/c). Antibody Properties: Cytotoxic and staining antibody. For staining, use 10ml/1,000,000 cells. Titer for cytotoxicity should be determined by the investigator.
products categories :
MONOCLONAL/POLYCLONAL ANTIBODIES, MISCELLANEOUS ANTIBODIES; Monoclonal Antibodies
products description :
Introduction: MHC Class I is a membrane spanning molecule consisting of 2 proteins. MHC Class I is just about 350 amino acids in length, with roughly 75 amino acids at the carboxylic end comprising the transmembrane and cytoplasmic portions. The remaining 270 amino acids, are divided into three globular domains labeled Alpha-1, Alpha-2 and Alpha-3 prime, with Alpha-1 being closest to the amino terminus and Alpha-3 closest to the membrane. The second portion of the molecule is a small globular protein called Beta-2 Microglobulin It links primarily with the Alpha-3 prime domain and is essential for MHC stability. The MHC ability to show a vast range of antigenic peptides for T cell recognition needs a compromise between broad specificity and high affinity. Both MHC class I and MHC class II show an exceptional structure while the peptide main chain is tightly bound and peptide side chains show less restrictive interactions. It is primarily the peptide side-chain contacts and conformational variability that ensures that the peptide-MHC complex presents an antigenically unique surface to T cell receptors.
ncbi gi num :
82123757
ncbi acc num :
O98279
ncbi mol weight :
26,573 Da
size1 :
0.5 mg
price1 :
230 USD
size2 :
1 mg
price2 :
350
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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