catalog number :
MBS140067
products full name :
Mouse Anti Human CD5
products short name :
CD5
products name syn :
CD5 Antibody; CD5, Mouse Anti-Human; T-cell surface glycoprotein CD5; Lymphocyte antigen T1/Leu-1; CD5; T1; LEU1
other names :
T-cell surface glycoprotein CD5; T-cell surface glycoprotein CD5; T-cell surface glycoprotein CD5; CD5 antigen (p56-62); lymphocyte antigen T1/Leu-1; CD5 molecule; Lymphocyte antigen T1/Leu-1; CD_antigen: CD5
other gene names :
CD5; CD5; T1; LEU1; LEU1
uniprot entry name :
CD5_HUMAN
purity :
Ion exchange column.
concentration :
1mg/ml in PBS (after reconstitution).
storage stability :
Lyophilized: store at 4 degree C. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C.
other info2 :
Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Immunogen: Human PBL. Antibody Properties: Staining antibody. For staining, use 10 ul/1,000,000 cells. Available Conjugates: This antibody is only available in purified form.
products categories :
MONOCLONAL ANTIBODIES, ANTI-HUMAN LYMPHOCYTES; Monoclonal Antibodies; Anti Human Lymphocyte
products description :
Introduction: The T1/Leu1/CD5 molecule, a human T-cell surface glycoprotein of relative molecular mass (Mr) 67,000, has been implicated in the proliferative response of activated T cells and in T-cell helper function. Ly1 is the murine homolog. (In the mouse, lymphocyte surface antigens that are markers for function have been identified. Allelic forms are known and chromosomal assignment of the loci has been achieved. Ly1 is on mouse chromosome 19. Ly2 and Ly3 are on mouse chromosome 6. Ly5 is on mouse chromosome 1. Ly6 is on mouse chromosome 15.
ncbi acc num :
NP_055022.2
ncbi gb acc num :
NM_014207.3
ncbi mol weight :
54,578 Da
ncbi pathways :
B Cell Receptor Signaling Pathway (198909); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489)
uniprot summary :
CD5: a surface glycoprotein expressed on T cells and B-1 B cells. Rapidly recruited to the immunological synapse, lowering the response of the T cell antigen receptor. CD5 interacts with CD72/LYB-2. Promotes B-cell survival through stimulation of autocrine IL-10 production. Contains 3 SRCR domains. Protein type: Membrane protein, integral; Cell surface. Chromosomal Location of Human Ortholog: 11q13. Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane. Molecular Function: protein binding; transmembrane receptor activity; receptor activity; scavenger receptor activity. Biological Process: receptor-mediated endocytosis; cell proliferation; T cell costimulation; cell recognition