catalog number :
MBS140058
products full name :
Rat Anti Mouse LY6G
products short name :
[LY6G]
products name syn :
[LY6G Antibody; LY6G, Rat Anti Mouse Antibody; Lymphocyte antigen 6G; Ly-6G; Ly-6G.1; Ly6g; Gr1; Gr-1]
products gene name :
[LY6G]
purity :
Protein A column.
concentration :
1mg/ml in PBS (after reconstitution).
storage stability :
In lyophilized form, for long periods, store at 4 degree C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C. Antibody is shipped lyophilized at ambient temperature.
tested application :
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Cell Depletion
other info2 :
Reconstitution: Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Immunogen: Ly-6G-transfected cell line. Antibody Properties: This antibody recognizes only Ly-6G which is expressed on most myeloid cells in the bone marrow and all peripheral granulocytes. For flow cytometry, use 10 ul/106 cells. Exact titer for cell depletion in vivo (cytotoxicity) should be determined by the investigator. Available Conjugates: This antibody is also available conjugated to biotin and FITC.
products categories :
MONOCLONAL/POLYCLONAL ANTIBODIES, MISCELLANEOUS ANTIBODIES; Monoclonal Antibodies
products description :
Introduction: Myeloid differentiation antigen Gr1 (Ly6G) is a GPI-anchored protein, which is briefly expressed on monocytes in the bone marrow. The level of the Ly6G expression in the bone marrow completely correlates with granulocyte differentiation and maturation. Ly6G ligation on murine neutrophils inhibits neutrophil recruitment, thus providing the first evidence of a function for the Ly6G molecule. Ly6G is seen primarily on neutrophils, also in a subgroup of eosinophils, differentiating pre-monocytes and plasmacytoid dendritic cells.