catalog number :
MBS140034
products full name :
Rat Anti Mouse CD80
products short name :
CD80
products name syn :
CD80 Antibody; B7-1 (CD80), Rat Anti-Mouse; LAB7; CD28LG; CD28LG1; CD28LG1; B71
other names :
CD80; CD80; T-lymphocyte activation antigen CD80; CD80
products gene name :
CD80
other gene names :
CD80; CD80; B7-1
uniprot entry name :
Q8WMZ2_PIG
purity :
Ion exchange column.
concentration :
1mg/ml in PBS (after reconstitution).
storage stability :
Lyophilized: store at 4 degree C. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C.
other info2 :
Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Immunogen: Purified mouse LPS-activated B cells. Antibody Properties: Blocking and staining antibody. For staining, use 10 ul/1,000,000 cells. Titer for blocking T cell activation should be determined by the investigator. Available Conjugates: This antibody is only available as purified antibody.
products categories :
MONOCLONAL ANTIBODIES, ANTI-MOUSE LYMPHOCYTES; Monoclonal Antibodies; Anti Mouse Lymphocyte
products description :
Introduction: The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells CD-80 is involved in the costimulatory signal essential for t- lymphocyte activation. t-cell proliferation and cytokine production is induced by the binding of cd28 or ctla-4 to this receptor.
ncbi acc num :
AAL58443.1
ncbi mol weight :
33,275 Da
ncbi pathways :
Adaptive Immune System Pathway 1125065!!Allograft Rejection Pathway 84530!!Allograft Rejection Pathway 535!!Autoimmune Thyroid Disease Pathway 84528!!Autoimmune Thyroid Disease Pathway 533!!CD28 Co-stimulation Pathway 1125072!!CD28 Dependent PI3K/Akt Signaling Pathway 1125073!!CD28 Dependent Vav1 Pathway 1125074!!CTLA4 Inhibitory Signaling Pathway 1125075!!Cell Adhesion Molecules (CAMs) Pathway 84481