Mouse Anti Human Vascular Endothelial Growth Factor | MyBioSource MBS140026 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Mouse Anti Human Vascular Endothelial Growth Factor

catalog :

MBS140026

quantity :

0.5 mg

price :

230 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

NYRhVEGF

reactivity :

human

application :

western blot, ELISA, immunoprecipitation, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS140026

products type :

Antibody

products full name :

Mouse Anti Human Vascular Endothelial Growth Factor

products short name :

Vascular Endothelial Growth Factor

products name syn :

VEGF Antibody; Vascular Endothelial Cell Growth Factor, Mouse Anti-Human; Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF; VEGF; MGC70609

other names :

vascular endothelial growth factor A isoform a; Vascular endothelial growth factor A; vascular endothelial growth factor A; vascular permeability factor; vascular endothelial growth factor A; Vascular permeability factor; VPF

products gene name :

VEGF

other gene names :

VEGFA; VEGFA; VPF; VEGF; MVCD1; VEGF; VEGF-A; VPF

uniprot entry name :

VEGFA_HUMAN

clonality :

Monoclonal

isotype :

IgM

clone :

NYRhVEGF

host :

Mouse

sequence length :

412

purity :

Boric acid precipitation Protein concentration1mg/ml in PBS (after reconstitution).

storage stability :

In lyophilized form, for long periods, store at 4 degree C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C. Antibody is shipped lyophilized at ambient temperature.

tested application :

ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP)

app notes :

Direct ELISA, Western Blot, Immunoprecipitation. By direct ELISA, 1:10,000 dilution will yield 0.15 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig.

other info2 :

Reconstitution: Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Immunogen: r.HumanVEGF.

products categories :

ANTI-HUMAN CYTOKINES; Monoclonal Antibodies; Anti Human Cytokine

products description :

Introduction: Vascular endothelial growth factoris an important signaling proteininvolved in both vasculogenesisand angiogenesis. As its name implies, VEGF activity has been mostly studied on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g. stimulation monocyte/macrophagemigration, neurons, cancer cells, kidney epithelial cells).VEGF mediates increased vascular permeability, induces angiogenesis, vasculogenesis and endothelial cell growth, promotes cell migration, and inhibits apoptosis. In vitro, VEGF has been shown to stimulate endothelial cell mitogenesisand cell migration. VEGF is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor.Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy.

ncbi gi num :

76781480

ncbi acc num :

NP_001020537.2

ncbi gb acc num :

NM_001025366.2

ncbi mol weight :

34,406 Da

ncbi pathways :

Angiogenesis Pathway (198772); Axon Guidance Pathway (105688); Bladder Cancer Pathway (83115); Bladder Cancer Pathway (527); Cellular Response To Hypoxia Pathway (645259); Cellular Responses To Stress Pathway (645258); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Developmental Biology Pathway (477129); EPH-Ephrin Signaling Pathway (1127691)

ncbi summary :

This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, Jul 2008]

size1 :

0.5 mg

price1 :

230 USD

size2 :

1 mg

price2 :

350

more info or order :

MyBioSource product webpage