catalog number :
MBS140003
products full name :
Mouse Anti Human Interleukin-2
products short name :
Interleukin-2
products name syn :
IL 2 Antibody; Interleukin-2, Mouse Anti-Human; T-cell growth factor (TCGF); Aldesleukin; Lymphokine; IL-2
other names :
IL-2, partial; IL-2 protein; IL-2 protein
products gene name :
IL-2
uniprot entry name :
O95974_HUMAN
reactivity :
A certain degree of functional cross reactivity with murine IL-2 was reported by some investigators.
concentration :
1mg/ml in PBS (after reconstitution).
storage stability :
In lyophilized form, for long periods, store at 4 degree C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C. Antibody is shipped lyophilized at ambient temperature.
tested application :
ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Blocking T Cell Poroliferation
app notes :
Direct ELISA, Western Blot, Immunoprecipitation, immunohistochemistry, blocking T cell poroliferation.
other info1 :
Titer By direct ELISA: 1:10,000 dilution will yield 0.4 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories). 1:50 dilution will block 70-80% of CTLL proliferative response to 50 units of r.human IL-2.
other info2 :
Reconstitution: Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Immunogen: r.Human IL-2.
products categories :
ANTI-HUMAN CYTOKINES; Monoclonal Antibodies; Anti Human Cytokine
products description :
Introduction: IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
ncbi acc num :
CAA07317.1
ncbi mol weight :
4,762 Da