product summary
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company name :
MyBioSource
product type :
protein
product name :
FITC Labeled Bovine Fibrinogen
catalog :
MBS135651
quantity :
10 mg
price :
225 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS135651
products type :
Protein
products full name :
FITC Labeled Bovine Fibrinogen
products short name :
FITC Labeled Bovine Fibrinogen
other names :
fibrinogen alpha chain; Fibrinogen alpha chain; fibrinogen alpha chain; fibrinogen A-alpha chain; fibrinogen, alpha polypeptide; fibrinogen alpha chain
products gene name :
FGA
other gene names :
FGA; FGA
uniprot entry name :
FIBA_BOVIN
host :
Bovine plasma
sequence length :
615
purity :
>95% by SDS-PAGE analysis
form :
Frozen liquid
concentration :
11.1mg/ml; 80% Clottable
storage stability :
Store at -70 degree C; Protect from light. Shelf Life: 3 years from delivery
other info1 :
Volume: 3.6ml
other info2 :
Buffer: 0.02M Sodium Citrate-HCl; pH 7.4. Extinction Coefficient: 1.51
products categories :
Fibrinogen; Bovine Fibrinogen
products description :
Bovine fibrinogen amino terminal labeled with fluorescein isothiocyanate (FITC). Prepared from fresh bovine plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography. Thaw at 37C without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37 degree C, aliquot and flash freeze unused portion.
ncbi gi num :
75812954
ncbi acc num :
NP_001028798.1
ncbi gb acc num :
NM_001033626.1
uniprot acc num :
P02672
ncbi mol weight :
330,000
ncbi pathways :
Complement And Coagulation Cascades Pathway (84312); Complement And Coagulation Cascades Pathway (484)
uniprot summary :
Function: Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation. Subunit structure: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain. Subcellular location: Secreted. Domain: A long coiled coil structure formed by 3 polypeptide chains connects the central nodule to the C-terminal domains (distal nodules). The long C-terminal ends of the alpha chains fold back, contributing a fourth strand to the coiled coil structure. Post-translational modification: Conversion of fibrinogen to fibrin is triggered by thrombin, which cleaves fibrinopeptides A and B from alpha and beta chains, and thus exposes the N-terminal polymerization sites responsible for the formation of the soft clot. The soft clot is converted into the hard clot by factor XIIIA which catalyzes the epsilon-(gamma-glutamyl)lysine cross-linking between gamma chains (stronger) and between alpha chains (weaker) of different monomers.Forms F13A-mediated cross-links between a glutamine and the epsilon-amino group of a lysine residue, forming fibronectin-fibrinogen heteropolymers.
size1 :
10 mg
price1 :
225 USD
size2 :
40 mg
price2 :
590
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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