product summary
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company name :
MyBioSource
product type :
protein
product name :
Prekallikrein, Human Plasma
catalog :
MBS135646
quantity :
1 mg
price :
580 USD
more info or order :
product information
catalog number :
MBS135646
products type :
Protein
products full name :
Prekallikrein, Human Plasma
products short name :
Prekallikrein, Human Plasma
other names :
kallikrein-1 preproprotein; Kallikrein-1; kallikrein-1; tissue kallikrein; glandular kallikrein 1; kallikrein serine protease 1; kallikrein 1, renal/pancreas/salivary; kidney/pancreas/salivary gland kallikrein; kallikrein 1; Kidney/pancreas/salivary gland kallikrein; Tissue kallikrein
products gene name :
KLK1
other gene names :
KLK1; KLK1; hK1; KLKR; Klk6
uniprot entry name :
KLK1_HUMAN
host :
Human plasma
sequence length :
262
purity :
>95% by SDS-PAGE analysis
form :
Frozen liquid
concentration :
0.833 mg/ml. Aliquot: 1 x 1.0mg. Volume: 1.2 ml
storage stability :
Store at -70 degree C. Shelf Life: 3 years from delivery
other info2 :
Buffer: 0.004M Sodium Acetate; 0.15M NaCl; pH 5.3. Extinction Coefficient: 1.17
products categories :
Kallikrein/Prekallikrein; Human Prekallikrein
products description :
Zymogen precursor of the plasma serine protease kallikrein. >95percent pure by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol.
ncbi gi num :
4504875
ncbi acc num :
NP_002248.1
ncbi gb acc num :
NM_002257.2
uniprot acc num :
P06870
ncbi mol weight :
86,000
ncbi pathways :
Blood Clotting Cascade Pathway (198840); Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213307); Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213276); Metabolism Of Proteins Pathway (106230); Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway (105908)
ncbi summary :
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq, Jul 2008]
uniprot summary :
KLK1: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Belongs to the peptidase S1 family. Kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.4.21.35; Protease. Chromosomal Location of Human Ortholog: 19q13.3. Cellular Component: nucleus. Molecular Function: serine-type endopeptidase activity. Biological Process: proteolysis. Disease: Kallikrein, Decreased Urinary Activity Of
size1 :
1 mg
price1 :
580 USD
size2 :
5 mg
price2 :
2260
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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