Rabbit anti human fibronectin, affinity purified | MyBioSource MBS135443 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit anti human fibronectin, affinity purified

catalog :

MBS135443

quantity :

0.1 mg

price :

425 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS135443

products type :

Antibody

products full name :

Rabbit anti human fibronectin, affinity purified

products short name :

[fibronectin, affinity purified]

other names :

[fibronectin isoform 3 preproprotein; Fibronectin; fibronectin; cold-insoluble globulin; migration-stimulating factor; fibronectin 1; Cold-insoluble globulin]

products gene name :

[FN1]

other gene names :

[FN1; FN1; FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; FN; FN; CIG]

uniprot entry name :

FINC_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

rabbit

reactivity :

Human

sequence length :

2355

purity :

Affinity purification

form :

Frozen liquid

concentration :

0.46mg/ml

storage stability :

Store at -70 degree C. Shelf Life: 5 years from delivery. Shipping: Ships with dry ice.

tested application :

ELISA (EIA), Western Blot (WB)

other info1 :

Titer: 1:40,000. Immunogen: Full length native protein (purified) (Human). Target Information: Recognises Fibronectin. Target Molecular Weight: 220,000

other info2 :

Buffer: 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6. Extinction Coefficient: 1.36

products categories :

Fibronectin; Polyclonal Antibodies to Human Fibronectin

products description :

Polyclonal antibody (host rabbit). Affinity purified by immobilized human fibronectin.

ncbi gi num :

16933542

ncbi acc num :

NP_002017.1

ncbi gb acc num :

NM_002026.2

uniprot acc num :

P02751

ncbi mol weight :

160,000

ncbi pathways :

Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Angiopoietin Receptor Tie2-mediated Signaling Pathway (137917); Bacterial Invasion Of Epithelial Cells Pathway (149807); Bacterial Invasion Of Epithelial Cells Pathway (148661); Cell Surface Interactions At The Vascular Wall Pathway (106062); ECM-receptor Interaction Pathway (83068); ECM-receptor Interaction Pathway (479); Extracellular Matrix Organization Pathway (576262); Fibronectin Matrix Formation Pathway (771601)

ncbi summary :

This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

uniprot summary :

FN1: Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Defects in FN1 are the cause of glomerulopathy with fibronectin deposits type 2 (GFND2); also known as familial glomerular nephritis with fibronectin deposits or fibronectin glomerulopathy. GFND is a genetically heterogeneous autosomal dominant disorder characterized clinically by proteinuria, microscopic hematuria, and hypertension that leads to end-stage renal failure in the second to fifth decade of life. 15 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Cell adhesion; Secreted, signal peptide; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 2q34. Cellular Component: extracellular matrix; extracellular space; apical plasma membrane; fibrinogen complex; extracellular region; ER-Golgi intermediate compartment; basal lamina. Molecular Function: integrin binding; heparin binding; collagen binding; protein binding; protease activator activity; protease binding. Biological Process: integrin activation; platelet activation; extracellular matrix organization and biogenesis; positive regulation of axon extension; extracellular matrix disassembly; regulation of cell shape; platelet degranulation; cell-substrate junction assembly; calcium-independent cell-matrix adhesion; acute-phase response; response to wounding; angiogenesis; peptide cross-linking; cell adhesion; blood coagulation; leukocyte migration. Disease: Glomerulopathy With Fibronectin Deposits 2; Plasma Fibronectin Deficiency

size1 :

0.1 mg

price1 :

425 USD

size2 :

1 mg

price2 :

2785

more info or order :

MyBioSource product webpage