product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Mouse Wiskott-Aldrich syndrome protein family member 2 (Wasf2)
catalog :
MBS1353669
quantity :
0.5 mg (E-Coli)
price :
1285 USD
more info or order :
product information
catalog number :
MBS1353669
products type :
Recombinant Protein
products full name :
Recombinant Mouse Wiskott-Aldrich syndrome protein family member 2 (Wasf2)
products short name :
Wiskott-Aldrich syndrome protein family member 2 (Wasf2)
products name syn :
Wiskott-Aldrich syndrome protein family member 2; WASP family protein member 2; Protein WAVE-2
other names :
wiskott-Aldrich syndrome protein family member 2; Wiskott-Aldrich syndrome protein family member 2; wiskott-Aldrich syndrome protein family member 2; protein WAVE-2; WASP family protein member 2; WAS protein family, member 2; Protein WAVE-2
products gene name :
Wasf2
products gene name syn :
Wasf2; Wave2
other gene names :
Wasf2; Wasf2; WAVE2; AW742646; D4Ertd13e; Wave2; WASP family protein member 2
uniprot entry name :
WASF2_MOUSE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-497
sequence length :
497
sequence :
MPLVTRNIEP RHLCRQTLPS DTSELECRTN ITLANVIRQL GSLSKYAEDI FGEICTQASA FASRVNSLAE RVDRVQVKVT QLDPKEEEVS LQGINTRKAF RSSTTQDQKL FDRNSLPVPV LETYNSCDAP PPLNNLSPYR DDGKEALKFY TNPSYFFDLW KEKMLQDTKD IMKEKRKHRK EKKDNPNRGN VNPRKIKTRK EEWEKMKMGQ EFVESKERLG PSGYSSTLVY QNGSIGSVEN VDAASYPPPP QSDSASSPSP SFSEDNLPPP PAEFSYPADN QRGSVLAGPK RTSMVSPSHP PPAPPLSSPP GPKPGFAPPP APPPPPPMSV PPPLPSMGFG SPGTPPPPSP PSFPPHPDFA APPPPPPPPA ADYPMPPPPL SQPSGGAPPP PPPPPPPGPP PLPFSGADGQ PAAPPPPPPS EATKPKSSLP AVSDARSDLL SAIRQGFQLR RVEEQREQEK RDVVGNDVAT ILSRRIAVEY SDSEDDSSEF DEDDWSD
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Mus musculus (Mouse)
products description :
Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity).
ncbi gi num :
23510313
ncbi acc num :
NP_700472.1
ncbi gb acc num :
NM_153423.6
uniprot acc num :
Q8BH43
ncbi mol weight :
58kD
ncbi pathways :
Adherens Junction Pathway (83267); Adherens Junction Pathway (481); Bacterial Invasion Of Epithelial Cells Pathway (149817); Bacterial Invasion Of Epithelial Cells Pathway (148661); Fc Gamma R-mediated Phagocytosis Pathway (114297); Fc Gamma R-mediated Phagocytosis Pathway (106590); Regulation Of Actin Cytoskeleton Pathway (198389); Regulation Of Actin Cytoskeleton Pathway (83286); Regulation Of Actin Cytoskeleton Pathway (500); Salmonella Infection Pathway (375174)
uniprot summary :
WAVE2: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Binds actin and the Arp2/3 complex. Interacts with BAIAP2. Component of the WAVE2 complex composed of ABI1, CYFIP1/SRA1, NCKAP1/NAP1 and WASF2/WAVE2. Directly interacts with BRK1. Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle. Belongs to the SCAR/WAVE family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; Actin-binding. Cellular Component: ruffle; cytoskeleton; lamellipodium; cytoplasm; early endosome; intercellular junction; intracellular. Molecular Function: protein binding; protein complex binding; actin binding. Biological Process: lamellipodium biogenesis; negative regulation of stress fiber formation; actin filament-based movement; ameboidal cell migration; Rac protein signal transduction; endocytosis; angiogenesis; actin cytoskeleton organization and biogenesis; cell motility
size1 :
0.5 mg (E-Coli)
price1 :
1285 USD
size2 :
0.05 mg (Baculovirus)
price2 :
1285
size3 :
0.5 mg (Yeast)
price3 :
1500
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1500
size5 :
1 mg (E-Coli)
price5 :
2105
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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