antibody

Sheep anti human CRP IgG fraction, HRP labeled

MBS135360

1 mg

345 USD

polyclonal

sheep

HRP

ELISA, enzyme immunoassay

Antibody

Sheep anti human CRP IgG fraction, HRP labeled

[CRP IgG fraction, HRP labeled]

[C-reactive protein; C-reactive protein; C-reactive protein; pentraxin 1; C-reactive protein, pentraxin-related]

[CRP]

[CRP; CRP; PTX1; PTX1]

CRP_HUMAN

Polyclonal

IgG

Sheep

Human

224

IgG fraction

Frozen liquid

1.155 mg/ml

Store at -70°C. Ships with Dry ice. Shelf Life: 5 years from delivery

ELISA (EIA)

Source: Sheep serum. Immunogen: Full length native protein (purified from pleural fluid) (Human). Target Information: Recognises C-Reactive Protein (CRP). Target Molecular Weight: 115000

Buffer: PBS, pH 7.4; 1% BSA, 0.01% Thimerosal. Extinction Coefficient: 1.36. Preservative: Thimerosal

C-Reactive Protein (CRP); Polyclonal Antibodies to Human CRP

Horseradish peroxidase labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.

55770842

NP_000558.2

NM_000567.2

P02741

160,000

Classical Antibody-mediated Complement Activation Pathway (106409); Complement Cascade Pathway (106405); Creation Of C4 And C2 Activators Pathway (106407); IL6-mediated Signaling Events Pathway (137932); Immune System Pathway (106386); Initial Triggering Of Complement Pathway (106406); Innate Immune System Pathway (106387); Selenium Pathway (198825)

The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]

CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1q23.2. Cellular Component: extracellular space; growth cone; extracellular region; filopodium. Molecular Function: choline binding; protein binding; protein homodimerization activity; low-density lipoprotein receptor binding; complement component C1q binding; virion binding; low-density lipoprotein binding; cholesterol binding; calcium ion binding. Biological Process: protein polymerization; defense response to Gram-positive bacterium; response to ethanol; wound healing; negative regulation of vasodilation; positive regulation of superoxide release; response to lead ion; acute-phase response; response to hypoxia; opsonization; inflammatory response; complement activation, classical pathway; aging

1 mg

345 USD

10 mg

2210