catalog number :
MBS1350503
products type :
Recombinant Protein
products full name :
Recombinant Human Sialic acid-binding Ig-like lectin 15
products short name :
Sialic acid-binding Ig-like lectin 15
products name syn :
CD33 antigen-like 3
other names :
sialic acid-binding Ig-like lectin 15; Sialic acid-binding Ig-like lectin 15; sialic acid-binding Ig-like lectin 15; sialic acid binding Ig like lectin 15; CD33 antigen-like 3
products gene name :
SIGLEC15
other gene names :
SIGLEC15; SIGLEC15; CD33L3; HsT1361; SIGLEC-15; CD33L3; Siglec-15
uniprot entry name :
SIG15_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
20-263
sequence :
FVRTKIDTTENLLNTEVHSSPAQRWSMQVPPEVSAEAGD
AAVLPCTFTHPHRHYDGPLTAIWRAGEPYAGPQVFRCAA
ARGSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALAD
DRRYFCRVEFAGDVHDRYESRHGVRLHVTAAPRIVNISV
LPSPAHAFRALCTAEGEPPPALAWSGPALGNSLAAVRSP
REGHGHLVTAELPALTHDGRYTCTAANSLGRSEASVYLF
RFHGASGAST
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info2 :
Species: Homo sapiens (Human)
products description :
Binds sialylated glycoproteins.
products references :
Siglec-15: an immune system Siglec conserved throughout vertebrate evolution."
Angata T., Tabuchi Y., Nakamura K., Nakamura M.
Glycobiology 17:838-846(2007)
ncbi acc num :
NP_998767.1
ncbi gb acc num :
NM_213602.2
ncbi mol weight :
42.54kD
ncbi pathways :
DAP12 Interactions Pathway (1269283); Immune System Pathway (1269170); Innate Immune System Pathway (1269203)
uniprot summary :
CD33L3: Binds sialylated glycoproteins. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 18q12.3. Cellular Component: integral to membrane; plasma membrane; protein complex. Biological Process: innate immune response; regulation of actin cytoskeleton organization and biogenesis; regulation of bone resorption
size2 :
0.02 mg (Mammalian-Cell)
size4 :
0.05 mg (Mammalian-Cell)