product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal to mouse uPA
catalog :
MBS135040
quantity :
1 mg
price :
860 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[H77A1]
reactivity :
mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS135040
products type :
Antibody
products full name :
Mouse monoclonal to mouse uPA
products short name :
[uPA]
other names :
[urokinase-type plasminogen activator; Urokinase-type plasminogen activator; urokinase-type plasminogen activator; U-plasminogen activator; plasminogen activator, urokinase]
products gene name :
[PLAU]
other gene names :
[Plau; Plau; uPA; u-PA; U-plasminogen activator; uPA]
uniprot entry name :
UROK_MOUSE
clonality :
m
isotype :
IgG
clone :
[H77A1]
host :
mouse
reactivity :
Mouse, rat
sequence length :
433
purity :
IgG fraction
form :
Frozen liquid
concentration :
3.42 mg/ml. Volume: 0.292 ml. Aliquot: 1 x 1.0mg
storage stability :
Store at -70 degree C. Shelf Life: 5 years from delivery
tested application :
ELISA (EIA), Capture, Western Blot (WB), Immunohistochemistry (IHC) Paraffin
other info1 :
Immunogen: Recombinant full length wild-type mouse protein (Glycosylated). Target Information: Recognises Urokinase (uPA). Target Molecular Weight: 44000
other info2 :
Buffer: 0.05M Sodium Phosphate; 0.15M NaCl; pH 7.4. Extinction Coefficient: 1.36
products categories :
Urokinase (uPA); Monoclonal Antibodies to Mouse uPA
products description :
Capture monoclonal antibody produced in mouse. IgG fraction purified by immobilized Protein A. Isotype IgG.
ncbi gi num :
6679377
ncbi acc num :
NP_032899.1
ncbi gb acc num :
NM_008873.3
uniprot acc num :
P06869
ncbi mol weight :
160,000
ncbi pathways :
Blood Clotting Cascade Pathway (198388); Complement And Coagulation Cascades Pathway (198335); Complement And Coagulation Cascades Pathway (83270); Complement And Coagulation Cascades Pathway (484); Dissolution Of Fibrin Clot Pathway (765587); Endochondral Ossification Pathway (198336); Hemostasis Pathway (765555); NF-kappa B Signaling Pathway (634537); Proteoglycans In Cancer Pathway (782024); Proteoglycans In Cancer Pathway (782054)
uniprot summary :
uPA: Specifically cleave the zymogen plasminogen to form the active enzyme plasmin. Defects in PLAU are the cause of Quebec platelet disorder (QPD). QPD is an autosomal dominant bleeding disorder due to a gain-of-function defect in fibrinolysis. Although affected individuals do not exhibit systemic fibrinolysis, they show delayed onset bleeding after challenge, such as surgery. The hallmark of the disorder is markedly increased PLAU levels within platelets, which causes intraplatelet plasmin generation and secondary degradation of alpha-granule proteins. Belongs to the peptidase S1 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Protease; EC 3.4.21.73; Secreted; Motility/polarity/chemotaxis. Cellular Component: extracellular space; focal adhesion; cell surface; membrane; extracellular region. Molecular Function: peptidase activity; hydrolase activity; serine-type peptidase activity; serine-type endopeptidase activity; catalytic activity. Biological Process: wound healing; smooth muscle cell migration; skeletal muscle regeneration; positive regulation of smooth muscle cell migration; proteolysis; regulation of cell proliferation; regulation of cell adhesion mediated by integrin; fibrinolysis; regulation of smooth muscle cell migration; positive regulation of cell proliferation; response to hypoxia; regulation of receptor activity; angiogenesis
size1 :
1 mg
price1 :
860 USD
size2 :
10 mg
price2 :
5240
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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