catalog number :
MBS1339290
products type :
Recombinant Protein
products full name :
Recombinant Danio rerio Signal peptide, CUB and EGF-like domain-containing protein 2 (scube2), partial
products short name :
[Signal peptide, CUB and EGF-like domain-containing protein 2 (scube2)]
other names :
[signal peptide, CUB and EGF-like domain-containing protein 2; Signal peptide, CUB and EGF-like domain-containing protein 2; signal peptide, CUB and EGF-like domain-containing protein 2; signal peptide, CUB domain, EGF-like 2; Protein You]
products gene name :
[scube2]
products gene name syn :
[scube2]
other gene names :
[scube2; scube2; you; wu:fc27f08; you]
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
[28-426. Partial, Contains 9 EGF-like domains]
sequence :
NTDQCAEGSDACHIDAICQNTPTSYKCTCKTGFKGDGKH
CEDIDECDVEYNGGCVHECNNIPGNYRCTCLDGFHLAHD
GHNCLDVDECVFNNGGCQHVCVNTMGSYECRCKQGFFLS
DNQHTCIHRSVEGLSCMNKEHGCGHICKESPKGGVACEC
RPGFELAKNQRGCILTCNHGNGGCQHICEDTEQGPICRC
HVRYMLHADGRTCVERDEMAPTAPDHNATSLAEVDKRVK
RRLLMETCAVNNGGCDSTCKDTSTGVRCSCPVGFTLQPD
GKSCKDIDECELHNGGCDHYCRNTIGSFECSCRKGFKLL
TDERSCQDIDECFFERTCDHTCVNSPGSFQCVCNKGYTL
YGLAHCGDINECSFNNGGCEHTCENTMGSFGCHCRAGYK
LHWNKKDCI
form :
Liquid containing glycerol
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Zebrafish
other info2 :
Storage Buffer: Tris-based buffer, 50% glycerol
ncbi acc num :
NP_001014813.1
ncbi gb acc num :
NM_001014813.1
ncbi mol weight :
112,176 Da
uniprot summary :
Lipid-binding protein required for SHH long-range signaling by binding to the dually lipid-modified SHH (ShhNp) and by promoting ShhNp mobilization, solubilization and release from the cell membrane. Acts by enhancing the proteolytic processing (shedding) of the lipid-modified N- and C- terminal of ShhNp at the cell surface. Synergizes with DISP1 to cause a increase in SHH secretion. Probable cell surface coreceptor for VEGFR2 involved in VEGFR2-mediated angiogenesis.
size3 :
0.05 mg (Baculovirus)
size7 :
0.05 mg (Mammalian-Cell)
size8 :
0.1 mg (Baculovirus)
size11 :
0.5 mg (Baculovirus)
size12 :
0.1 mg (Mammalian-Cell)
size14 :
1 mg (Baculovirus)