product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human GDNF family receptor alpha-4 (GFRA4)
catalog :
MBS1327360
quantity :
0.5 mg (E-Coli)
price :
1010 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1327360
products type :
Recombinant Protein
products full name :
Recombinant Human GDNF family receptor alpha-4 (GFRA4)
products short name :
GDNF family receptor alpha-4 (GFRA4)
products name syn :
GDNF family receptor alpha-4; GDNF receptor alpha-4; GDNFR-alpha-4; GFR-alpha-4; Persephin receptor
other names :
GDNF family receptor alpha-4 isoform a; GDNF family receptor alpha-4; GDNF family receptor alpha-4; GFR-alpha-4; GDNFR-alpha-4; persephin receptor; GFR receptor alpha 4; GDNF receptor alpha-4; GDNF family receptor alpha 4; Persephin receptor
products gene name :
GFRA4
other gene names :
GFRA4; GFRA4; GDNF receptor alpha-4; GDNFR-alpha-4; GFR-alpha-4
uniprot entry name :
GFRA4_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
21-278
sequence length :
258
sequence :
VGGNRCVDAA EACTADARCQ RLRSEYVAQC LGRAAQGGCP RARCRRALRR FFARGPPALT HALLFCPCAG PACAERRRQT FVPSCAFSGP GPAPPSCLEP LNFCERSRVC RCARAAAGPW RGWGRGLSPA HRPPAAQASP PGLSGLVHPS AQRPRRLPAG PGRPLPARLR GPRGVPAGTA VTPNYVDNVS ARVAPWCDCG ASGNRREDCE AFRGLFTRNR CLDGAIQAFA SGWPPVLLDQ LNPQGDPEHS LLQVSSTG
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
products description :
Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.
ncbi gi num :
11545875
ncbi acc num :
NP_071422.1
ncbi gb acc num :
NM_022139.3
uniprot acc num :
Q9GZZ7
ncbi mol weight :
44kD
ncbi pathways :
Axon Guidance Pathway (105688); Developmental Biology Pathway (477129); NCAM Signaling For Neurite Out-growth Pathway (105689); NCAM1 Interactions Pathway (105697)
ncbi summary :
The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
GFRA4: Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla. Belongs to the GDNFR family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 20p13-p12. Cellular Component: extracellular space; plasma membrane. Molecular Function: glial cell line-derived neurotrophic factor receptor activity. Biological Process: negative regulation of ossification
size1 :
0.5 mg (E-Coli)
price1 :
1010 USD
size2 :
0.05 mg (Baculovirus)
price2 :
1010
size3 :
0.5 mg (Yeast)
price3 :
1240
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1240
size5 :
1 mg (E-Coli)
price5 :
1550
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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