product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Single-stranded DNA cytosine deaminase (AICDA)
catalog :
MBS1320088
quantity :
0.01 mg (Baculovirus)
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1320088
products type :
Recombinant Protein
products full name :
Recombinant Human Single-stranded DNA cytosine deaminase (AICDA)
products short name :
[Activation-induced cytidine deaminase (AICDA)]
other names :
[single-stranded DNA cytosine deaminase isoform 2; Single-stranded DNA cytosine deaminase; single-stranded DNA cytosine deaminase; activation induced cytidine deaminase; Activation-induced cytidine deaminase; AID; Cytidine aminohydrolase]
products gene name :
[AICDA]
products gene name syn :
[AICDA]
other gene names :
[AICDA; AICDA; AID; ARP2; CDA2; HIGM2; HEL-S-284; AID; AID]
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
[1-198. Full Length]
sequence :
MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSA
TSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRV
TWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCE
DRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHE
RTFKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRT
LGL
purity :
>85% (SDS-PAGE)
form :
Liquid containing glycerol
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Human
other info2 :
Storage Buffer: Tris-based buffer, 50% glycerol
products description :
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
ncbi gi num :
1057867551
ncbi acc num :
NP_001317272.1
ncbi gb acc num :
NM_001330343.1
uniprot acc num :
Q9GZX7
ncbi mol weight :
22,614 Da
ncbi pathways :
IL4-mediated Signaling Events Pathway (137933); Intestinal Immune Network For IgA Production Pathway (128760); Intestinal Immune Network For IgA Production Pathway (128670); Primary Immunodeficiency Pathway (83125); Primary Immunodeficiency Pathway (537); Pyrimidine Deoxyribonucleosides Degradation Pathway (782401); Pyrimidine Deoxyribonucleosides Salvage Pathway (782392); Pyrimidine Ribonucleosides Degradation Pathway (142431); Pyrimidine Ribonucleosides Salvage I Pathway (782394); Superpathway Of Pyrimidine Deoxyribonucleoside Salvage (782391)
ncbi summary :
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009]
uniprot summary :
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses (PubMed:18722174, PubMed:21385873, PubMed:21518874, PubMed:27716525). May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation (PubMed:21496894).
size1 :
0.01 mg (Baculovirus)
price1 :
205 USD
size2 :
0.02 mg (Baculovirus)
price2 :
305
size3 :
0.05 mg (Baculovirus)
price3 :
580
size4 :
0.05 mg (E-Coli)
price4 :
595
size5 :
0.05 mg (Yeast)
price5 :
745
size6 :
0.1 mg (Baculovirus)
price6 :
800
size7 :
0.2 mg (E-Coli)
price7 :
800
size8 :
0.5 mg (E-Coli)
price8 :
880
size9 :
0.2 mg (Yeast)
price9 :
1005
size10 :
0.5 mg (Baculovirus)
price10 :
1125
size11 :
0.5 mg (Yeast)
price11 :
1135
size12 :
0.05 mg (Mammalian-Cell)
price12 :
1200
size13 :
1 mg (E-Coli)
price13 :
1320
size14 :
1 mg (Baculovirus)
price14 :
1570
size15 :
1 mg (Yeast)
price15 :
1790
size16 :
0.1 mg (Mammalian-Cell)
price16 :
1955
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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