product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Septin-12 (41529)
catalog :
MBS1296532
quantity :
0.5 mg (E-Coli)
price :
1125 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1296532
products type :
Recombinant Protein
products full name :
Recombinant Human Septin-12 (41529)
products short name :
Septin-12 (41529)
products name syn :
Septin-12
other names :
septin-12 isoform 1; Septin-12; septin-12; septin 12
products gene name syn :
12-Sep
other gene names :
SEPT12; SEPT12; SPGF10
uniprot entry name :
SEP12_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-358
sequence length :
358
sequence :
MDPLRRSPSP CLSSQPSSPS TPPCEMLGPV GIEAVLDQLK IKAMKMGFEF NIMVVGQSGL GKSTMVNTLF KSKVWKSNPP GLGVPTPQTL QLHSLTHVIE EKGVKLKLTV TDTPGFGDQI NNDNCWDPIL GYINEQYEQY LQEEILITRQ RHIPDTRVHC CVYFVPPTGH CLRPLDIEFL QRLCRTVNVV PVIARADSLT MEEREAFRRR IQQNLRTHCI DVYPQMCFDE DINDKILNSK LRDRIPFAVV GADQEHLVNG RCVLGRKTKW GIIEVENMAH CEFPLLRDLL IRSHLQDLKD ITHNIHYENY RVIRLNESHL LPRGPGWVNL APASPGQLTT PRTFKVCRGA HDDSDDEF
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
products description :
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
ncbi gi num :
226492499
ncbi acc num :
NP_001147930.1
ncbi gb acc num :
NM_001154458.2
uniprot acc num :
Q8IYM1
ncbi mol weight :
69kD
ncbi pathways :
Bacterial Invasion Of Epithelial Cells Pathway (149807); Bacterial Invasion Of Epithelial Cells Pathway (148661)
ncbi summary :
This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
uniprot summary :
SEPT12: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). Defects in SEPT12 are the cause of spermatogenic failure 10 (SPGF10). An infertility disorder caused by spermatogenesis defects. It results in decreased sperm motility, concentration, and multiple sperm structural defects. The most prominent feature is a defective sperm annulus, a ring structure that demarcates the midpiece and the principal piece of the sperm tail. Belongs to the septin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Hydrolase; Cell cycle regulation; Cytoskeletal. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: microtubule cytoskeleton; perinuclear region of cytoplasm; stress fiber; spindle; midbody; cleavage furrow. Molecular Function: protein binding; GDP binding; protein homodimerization activity; GTP binding; phosphoinositide binding. Biological Process: cell division; cell cycle. Disease: Spermatogenic Failure 10
size1 :
0.5 mg (E-Coli)
price1 :
1125 USD
size2 :
0.05 mg (Baculovirus)
price2 :
1125
size3 :
0.5 mg (Yeast)
price3 :
1355
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1355
size5 :
1 mg (E-Coli)
price5 :
1785
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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