catalog number :
MBS129636
products full name :
ALDH1B1 Polyclonal Antibody
products short name :
ALDH1B1
products name syn :
ALDH5; ALDHX
other names :
Aldehyde dehydrogenase X, mitochondrial; Aldehyde dehydrogenase X, mitochondrial; aldehyde dehydrogenase X, mitochondrial; ALDH class 2; aldehyde dehydrogenase 5; acetaldehyde dehydrogenase 5; aldehyde dehydrogenase 1 family, member B1; Aldehyde dehydrogenase 5; Aldehyde dehydrogenase family 1 member B1
products gene name :
ALDH1B1
other gene names :
ALDH1B1; ALDH1B1; ALDH5; ALDHX; ALDH5; ALDHX
uniprot entry name :
AL1B1_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Affinity Purification
storage stability :
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200
other info1 :
Species: Human. Immunogen: Recombinant Protein
other info2 :
Immunogen: Recombinant protein of human ALDH1B1. Calculated Molecular Weight: 57kDa
products categories :
Polyclonal
products description :
This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems.
ncbi pathways :
Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); Ascorbate And Aldarate Metabolism Pathway (82932); Ascorbate And Aldarate Metabolism Pathway (293); Fatty Acid Degradation Pathway (82935); Fatty Acid Degradation Pathway (296); GABA Biosynthesis, Eukaryotes, Putrescine = GABA Pathway (413399); GABA Biosynthesis, Eukaryotes, Putrescine = GABA Pathway (468314); Glycerolipid Metabolism Pathway (82986); Glycerolipid Metabolism Pathway (361)
ncbi summary :
This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems. [provided by RefSeq, Jul 2008]
uniprot summary :
ALDH1B1: ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. Belongs to the aldehyde dehydrogenase family. Protein type: Oxidoreductase; Lipid Metabolism - fatty acid; Amino Acid Metabolism - tryptophan; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Amino Acid Metabolism - lysine degradation; Mitochondrial; Other Amino Acids Metabolism - beta-alanine; EC 1.2.1.3; Secondary Metabolites Metabolism - limonene and pinene degradation; Lipid Metabolism - glycerolipid; Amino Acid Metabolism - arginine and proline; Carbohydrate Metabolism - butanoate; Carbohydrate Metabolism - pyruvate; Amino Acid Metabolism - histidine; Carbohydrate Metabolism - ascorbate and aldarate; Carbohydrate Metabolism - propanoate. Chromosomal Location of Human Ortholog: 9p11.1. Cellular Component: nucleoplasm; mitochondrion; intracellular membrane-bound organelle; mitochondrial matrix. Molecular Function: aldehyde dehydrogenase (NAD) activity. Biological Process: ethanol catabolic process; carbohydrate metabolic process